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PHARMA FINALS JOURNALS > JOURNALS > Flashcards

JOURNALS Flashcards

1
Q

Main sites of gastric ulcer

A

Gastric angle, hiatal hernia, cardia, and gastric antum

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2
Q

Agent responsible for gastric ulcer

A

Helicobacter Pylori

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3
Q

Main clinical manifestation of gastric ulcer

A

Epigastric pain, dull pain, dull pain and burning sensation

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4
Q

The control group with gastric ulcer was treated with? (with dosage)

A

Omeprazole (2x a day, 20 mg each)

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5
Q

The experimental group with gastric ulcer was treated with? (with dosage)

A

Omeprazole + Amoxicillin (500 mg, x3 a day)

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6
Q

A patient with gastric ulcer and bleeding needs drug that are ?

A

Proton pump inhibitor or H2 receptor antagonist for hemostatic treatment

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7
Q

Experience group with gastric ulcer (n, remarkable effect, effective, invalid, total effective rate)

A

n = 44
Remarkable effect = 28
effective = 15
Invalid = 1
Total effective rate = 97.73

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8
Q

JOURNAL TITLE: Efficacy and ___ of ____ and ___ in the treatment of ____

A

Safety, Omeprazole, Amoxicillin, Gastric Ulcer

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9
Q

C positive rate of breath test in experimental group (n, before, after treatment)

(Gastric ulcer patients)

A

n = 44
Before treatment = 40
After treatment = 10

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10
Q

Control group (people with gastric ulcer) n, remarkable effect, Effective, Invalid, total effective rate

A

n = 44
remarkable effect = 24
effective = 13
Invalid = 7
total effective rate rate = 84.09

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11
Q

C positive rate of breath test in control group (n, before, after treatment)

(Gastric ulcer patients)

A

n = 44
before treatment = 38
After treatment = 21

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12
Q

Recurrence rate in control group (patients with gastric ulcer)

A

9

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13
Q

Recurrence rate in control group (patients with gastric ulcer)

A

2

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14
Q

It is a proton pump inhibitor drug that can decrease gastric acid secretion, avoid the degradation of blood clots in gastric ulcers

A

Omeprazole

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15
Q

Belongs to semi-synthetic penicillin, broad-spectrum antibiotic

A

Amoxicillin

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16
Q

Aggressive factors in Gastric Ulcer

A

HCl, Pepsin, gastric Acid

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17
Q

Protective factors in Gastric Ulcer

A

Mucus and Bicarbonate ions

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18
Q

Plays an important role in the synthesis of glycopeptides and construction of cell wall

A

Transpepitdation

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19
Q

Two times verus __ times daily ___ Dosing for the treatment of ___ in Females

A

Four, Cephalexin Uncomplicated Urinary Tract Infections

20
Q

One of the most common indications for outpatient antibiotic prescribing

A

Urinary Tract Infections

21
Q

Infectious Disease Society of America recommended the treatment of uncomplicated UTI with the following drugs: (first line empiric therapies

A

Trimethoprimsulfamethoxazole, nitrofurantoin, fosfomycin

22
Q

An oral first-generation cephalosporin

A

Cephalexin

23
Q

Bioavailability of Cephalexin

A

90%

24
Q

Common recommended dosage of cephalexin

A

250mg to 500mg every 6 hours (but 12 hours is adequate)

25
Q

Defined as Antibiotic treatment received at discharge from emergency department, urgent care site, or medical group office

A

Outpatient setting

26
Q

Serves as a surrogate for cephalexin susceptibility

A

Cefazolin

27
Q

Cefazolin susceptibility was determined by automated methods with the ?

A

Vitek 2 System (bioMerieux)

28
Q

Patients received cephalexin 500 mg 2 times a day or 4 times a day for 5 to 7 days as per the ?

A

ICD-10 diagnosis code for UTI

29
Q

Defined as the combined endpoint of (1) continued symptoms or necessitation of new therapy while taking the initially prescribed 5 to 7 days of treatment and (2) treatment of recurrent symptomatic UTI within 30 days

A

Treatment failure

30
Q

Primary objective of the study regarding 2 times and 4 times Cephalexin daily dosing

A

Compare treatment failure between patients treated for uUTI in the outpatient setting with oral cephalexin

31
Q

Is there any difference in the primary outcome of treatment failure between 2 groups of cephalexin?

A

No difference

32
Q

Most common adverse event reported in both groups of patients with UTI

A

Yeast infection

33
Q

Major benefit of reducing frequency of cephalexin for uUTI is?

A

Potential to improve patient adherence and satisfaction with treatment

34
Q

Oral ___/___ for the prevention of ___ following dental ___

A

Amoxicillin/Clavulanate, bacteremia, extractions

35
Q

A disease with an estimated annual incidence of 3-10 cases per 100,000 individuals and is characterized by high morbidity and mortality

A

Infectious endocarditis

36
Q

Mainly produced in relation to basic activities of daily life such as toothbrushing, odontogenic infections, and dental therapeutic procedures

A

Oral bacteremia

37
Q

Antibiotic of choice for patients who are not allergic to beta-lactams

A

Amoxicillin

38
Q

to determine the prevalence and duration of the bacteremia, ___ of peripheral venous blood was collected

A

10 ml

39
Q

The AMXG was given amoxicillin __ hours before the surgery

A

1-2 hours

40
Q

Most common pathogens in the oral cavity and responsible for most oral-maxillofacial infections

A

Staphylococcus aureus and Streptococcus viridans

41
Q

Primary cause of Infectious Endocarditis of oral origin

A

Streptococcus viridans

42
Q

It is a rare opportunistic infection but is associated with high mortality and morbidity

A

Mucormycosis

43
Q

Most common site of infection of mucormycosis

A

rhino-orbital-cerebral followed by pulmonary.

44
Q

It is a life threatening condition caused by Rhizopus microsporus.

A

Pulmonary mucormycosis

45
Q

Causative agent of pulmonary mucormycosis

A

Rhizopus microsporus

46
Q

what kind of diabetes did the patient with pulmonary mucormycosis have and how long did he have it?

A

Type 2 diabetes (2 years)

47
Q
A

PHARMA FINALS JOURNALS (1 decks)

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