Joints, Synovial Fluid and Cartilage Flashcards

1
Q

Name three Fibrous Joints (3)

A

Periodontal Ligament
Cranial Sutures
Interosseous Membranes

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2
Q

Primary Cartilaginous Joints only have what type of cartilage

A

Hyaline

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3
Q

Secondary Cartilaginous Joints only have what type of cartilage

A

Hyaline and Fibrocartilage

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4
Q

Synchondrosis are what type of Cartilaginous joint

A

Primary

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5
Q

Symphysis are what type of Cartilaginous Joint

A

Secondary

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6
Q

Articular Cartilage is also known as what type of cartilage

A

Hyaline

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7
Q

What is present in superficial/tangenital layer of articular cartilage

A

flattened chondrocytes that produce collagen and glycoproteins (e.g. lubricin)

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8
Q

what is present in transitional and deep layer of articular cartilage

A

round chondrocytes that produce proteoglycans such as aggrecan

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9
Q

How much water is in articular cartilage

A

75%

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10
Q

What are glycoproteins

A

(e.g. lubricin): proteins to which oligosaccharide chains are attached, i.e. more a protein than a carbohydrate!

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11
Q

what are proteoglycans

A

(e.g. aggrecan): proteins that are heavily glycosylated (= a protein core to which one or more GAGs attach), i.e. tend to be more carb than protein!

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12
Q

what are glycosaminoglycans

A

e.g. hyaluronic acid): long unbranched polysaccharides, which are highly polar and thus attract water

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13
Q

How much articular cartilage at patella

A

5-6mm

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14
Q

Does synovial have epithelial lining

A

No

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15
Q

What do Type A Synoviocytes do

A

Remove debris

Contribute to synovial fluid production

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16
Q

What are the main producer of Synovial Fluid

A

Type B Synoviocytes

17
Q

what is the turnover of synovial fluid

A

every 2 hours

18
Q

what is synovial fluid made up of

A

hyaluronic acid and lubricants

19
Q

With ageing what happens to synovial fluid

A

viscosity increases
reduced lubrication
water content decreases