Joint Physiology Flashcards
Example of fibrous joint?
skull
Which joints are classified into simple or compound?
synovial
What supplies chondrocytes with O2 and removes wate products?
synovial fluid
Is tehre a static poole of synovial fluid?
no
Is rapid movement associated with increased or decreased viscosity?
decreased
Is rapid movement associated with increased or decreased elasticity?
increased
What type of cartilage is articular cartilage normally?
hyaline
What type of collagen is there mainly in joints?
type II
Where is there the highest concentration of proteoglycan in the join?
middle and deep zone
What is responsible for compressive properties associated with load bearing?
proteoglycan
What is the ECM synthesized, organised, degradedand maintained by?
chondrocytes
What happens it he rate of ECM degraation exceeds rate of synthesis?
joint disease
Name anabolic factors.
TGF-b and IGF 1
Name catabolic factors.
TNF and IL-1
Name markers of cartilage degradations.
serum and synovial keratin sulphate
Type II collagen in synovial fluid