Joint Physiology Flashcards

1
Q

Example of fibrous joint?

A

skull

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2
Q

Which joints are classified into simple or compound?

A

synovial

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3
Q

What supplies chondrocytes with O2 and removes wate products?

A

synovial fluid

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4
Q

Is tehre a static poole of synovial fluid?

A

no

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5
Q

Is rapid movement associated with increased or decreased viscosity?

A

decreased

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6
Q

Is rapid movement associated with increased or decreased elasticity?

A

increased

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7
Q

What type of cartilage is articular cartilage normally?

A

hyaline

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8
Q

What type of collagen is there mainly in joints?

A

type II

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9
Q

Where is there the highest concentration of proteoglycan in the join?

A

middle and deep zone

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10
Q

What is responsible for compressive properties associated with load bearing?

A

proteoglycan

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11
Q

What is the ECM synthesized, organised, degradedand maintained by?

A

chondrocytes

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12
Q

What happens it he rate of ECM degraation exceeds rate of synthesis?

A

joint disease

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13
Q

Name anabolic factors.

A

TGF-b and IGF 1

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14
Q

Name catabolic factors.

A

TNF and IL-1

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15
Q

Name markers of cartilage degradations.

A

serum and synovial keratin sulphate

Type II collagen in synovial fluid

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16
Q

What does synovial cell profliferation and inflammation cause?

A

RA

17
Q

What shape are pseudo gout crystals?

A

rhomboid