Joint pain and swelling Flashcards

1
Q

What are the causes of joint pain and swelling in children

A

Infection: septic arthritis, osteomyelitis, viral arthritis
Trauma
Reactive arthritis
Haemophilia
Juvenile idiopathic arthritis/mixed connective tissue disease
Inflammatory disorders: Kawasaki disease, acute rheumatic fever, IBD
Vasculitis: Henoch-Schonlein purpura
Hypersensitivity: serum sickness
Malignancy: leukaemia, bone/soft tissue malignancy
Endocrine: Rickets
Ehlers Danlos

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2
Q

What are the red flags for acute joint pain and swelling

A

Fever
Night pain
Constant, severe pain
Refusal to weight bear
Unexplained bruising
Weight loss

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3
Q

What is Ehlers Danlos syndrome

A

Autosomal dominant condition that effects type II collagen

Tissue becomes more elastic → joint hypermobility and increased elasticity of the skin

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4
Q

What are the symptoms and signs of Ehlers Danlos

A

Repetitive injury
Recurrent subluxation/dislocation
Fatigue
Chronic pain
easy bruising or scarring
Hx SAH
Joint laxity
Hyperextensible skin
Aortic regurgitation, mitral valve prolapse, aortic dissection

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5
Q

Define Osgood-Schlatter Disease (OSD)

A

Osteochondritis (inflammation of cartilage or bone) at the tibial tuberosity / patellar tendon insertion at the knee

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6
Q

What is the aetiology and epidemiology of Osgood-Schlatter disease

A

May be caused by multiple small avulsion fractures from contractions of quadriceps muscle at their insertion into proximal tibial apophysis (ossification centre) – during growth spurt
Epidemiology = 4% of 10-15yo physically active

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7
Q

What are the symptoms of Osgood-Schlatter Disease (OSD)

A

Knee pain after exercise (gradual onset) → relieved by rest (Bilateral in 25-50%)
Localised tenderness and swelling over tibial tubercle/tuberosity
Hamstring tightness

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8
Q

What investigations should be done for Osgood-Schlatter disease

A

Clinical diagnosis
± XR (may be indicated by Ottawa knee rules): fragmentation of the tibial tubercle + overlying soft tissue swelling

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9
Q

What is the management of Osgood-Schlatter Disease (OSD)

A

Analgesia (paracetamol or NSAIDs)
Ice packs (intermittent and over the tibial tuberosity, 10-15 minutes, ≤3/day, including after exercise)
Protective knee pads (may relieve pain when kneeling)
Stretching
Reassure - This will resolve over time but may persist until the end of a growth spurt
Advise stopping/reducing all sporting activity (intensity, frequency or duration)
- Could change type of exercise to limit running and jumping requiring powerful quadriceps contraction
- As symptoms decrease, they can gradually increase their exercise levels
- Introduce low-impact quadriceps exercises (e.g. straight leg raises, cycling or swimming)

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10
Q

Define Chondromalacia patellae

A

Anterior knee pain from degeneration of articular cartilage on posterior surface of patella
Common in young adults from overuse in physical activity

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11
Q

What are the signs and symptoms of Chondromalacia patellae

A

Anterior knee pain
Pain exacerbated by running, climbing stairs or getting up from a chair
Painless passive movements but repeated extension → pain and grating sensation

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12
Q

What is the management for Chondromalacia patellae

A

Physiotherapy (strengthen the quadriceps)

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13
Q

What is Osteochondritis dissecans

A

Pathological process affecting the subchondral bone (most often the knee joint) with secondary effects on the joint cartilage

Reduced blood flow → cracks form in the articular cartilage and subchondral bone → avascular necrosis → fragmentation of bone and cartilage with free movement of fragments → activity-related joint pain

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14
Q

What are the signs and symptoms of Osteochondritis dissecans

A

Pain after exercise
Catching, locking and giving way
Swelling
Oedema
Joint effusion
Lateral femoral condyle: Feeling a painful ‘clunk’ when flexing or extending the knee
Medial femoral condyle:
- Tenderness on palpation of the articular cartilage of the medial femoral condyle when the knee is flexed
- Wilson’s sign: with the knee at 90° flexion and tibia internally rotated, the gradual extension of the joint leads to pain at about 30°, external rotation of the tibia at this point relieves the pain

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15
Q

What investigations should be done for Osteochondritis dissecans

A

X-ray (anteroposterior, lateral and tunnel views): may show the subchondral crescent sign or loose bodies

MRI: used to evaluate cartilage, visualise loose bodies, stage and assess the stability of the lesion

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16
Q

What is patellar subluxation

A

Medial knee pain due to lateral subluxation of the patella
Knee may give way

17
Q

What is patellar tendonitis

A

More common in athletic teenage boys
Chronic anterior knee pain that worsens after running
Tender below the patella on examination

18
Q

What does fever and localised joint swelling suggest in acute joint pain and what investigations should be done

A

Septic arthritis or osteomyelitis
FBC, CRP/ESR, blood cultures, X-ray

19
Q

What does recent infection suggest in acute joint pain and what investigations should be done

A

Reactive arthritis
FBC, CRP/ESR, stool/throat/urine culture

20
Q

What does features of rash and prolonged fever suggest in acute joint pain and what investigations should be done

A

Vasculitis e.g. Henoch-Schonlein purpura or Kawasaki disease
Urine micro and protein-creatinine ratio, U&Es, albumin, FBC, ESR/CRP, LFTs, echo

21
Q

What does bone pain, lymphadenopathy, and/or hepatomegaly suggest in acute joint pain and what investigations should be done

A

Leukaemia, neuroblastoma
FBC, ESR, x-ray, U&Es, LFTs

22
Q

What does migratory polyarthritis suggest in acute joint pain and what investigations should be done

A

rheumatic fever
FBC, CRP/ESR, throat swab, strep serology, ECG, echo

23
Q

What does symptoms duration >6 weeks + morning stiffness + reduced functioning suggest in acute joint pain

A

Juvenile arthritis