Joint Disorders Flashcards
1
Q
Hyaluronic acid
A
Produced by B cells
Non Newtonian thixotropic fluid
Viscosity decreases on force
2
Q
Conditions decreasing viscosity
A
Gout
Septic arthritis
Tb arthritis
RA
3
Q
Normal synovial fluid
A
Clear <200/microlt pmnc
4
Q
Inflammatory sf
A
Straw coloured or turbid 2000-50000 /miclt pmnc
5
Q
Pyogenic sf
A
> 50k / microlt (neutrophil)
6
Q
Tb sf
A
10k - 20k /microlt (lymphocytes)
7
Q
Zones of articulate cartilage
A
- Superficial tangential zone (High chondrocytes)
- Middle transitional zone ( lowest density chondrocytes)
- Deep zone (lowest water content)
- Calcified cartilage
8
Q
Osteoarthritis cartilage
A
Water increases
Proteoglycan same
Proteolytic enzymes increase
9
Q
OA Joints involved
A
DIP
PIP 1st CMC
10
Q
OA joints soared
A
Wrist
MCP
11
Q
RA Joints involved
A
Wrist
PIP
MCP (most common)
12
Q
RA Joint spared
A
DIP