Joint Disorders Flashcards

1
Q

Hyaluronic acid

A

Produced by B cells
Non Newtonian thixotropic fluid
Viscosity decreases on force

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2
Q

Conditions decreasing viscosity

A

Gout
Septic arthritis
Tb arthritis
RA

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3
Q

Normal synovial fluid

A

Clear <200/microlt pmnc

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4
Q

Inflammatory sf

A

Straw coloured or turbid 2000-50000 /miclt pmnc

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5
Q

Pyogenic sf

A

> 50k / microlt (neutrophil)

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6
Q

Tb sf

A

10k - 20k /microlt (lymphocytes)

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7
Q

Zones of articulate cartilage

A
  1. Superficial tangential zone (High chondrocytes)
  2. Middle transitional zone ( lowest density chondrocytes)
  3. Deep zone (lowest water content)
  4. Calcified cartilage
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8
Q

Osteoarthritis cartilage

A

Water increases
Proteoglycan same
Proteolytic enzymes increase

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9
Q

OA Joints involved

A

DIP

PIP 1st CMC

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10
Q

OA joints soared

A

Wrist

MCP

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11
Q

RA Joints involved

A

Wrist
PIP
MCP (most common)

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12
Q

RA Joint spared

A

DIP

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