JOHN WESt Flashcards

1
Q

FRC

A

functional residual capacity

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2
Q

Max inhalation

A

Total lung capacity

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3
Q

Max inhalation + Max exhalation

A

Vital capacity

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4
Q

Inhalation + exhalation

A

tidal volume

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5
Q

baseline of 0 + exhalation baseline

A

functional residual capacity

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6
Q

baseline of 0 + max exhalation baseline

A

residual volume

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7
Q

FRC by Helium dilution equation

A

C1 x V1 = C2 (V1+ FRC)

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8
Q

FRC by Plethysmograph

A

Box:
P1V1 = P2(V1 - delta V)

Lung:
P3 FRC = P4 (FRC + delta V)

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9
Q

Boyle’s law

A

Pressure x volume is a constant at constant temp

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10
Q

Lung disease can give a lower volume when using helium dilution.

A
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11
Q

Tidal vol x RR = Total vent

A
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12
Q

Dead space (150ml) x RR = Total dead space / min

A
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13
Q

Alveolar Vent = Total Vent - Total dead space

A
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14
Q

V (CO2) = alveolar vent x (%CO2/100)

A
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15
Q

P(CO2) = FCO2 x K

A

P(CO2) = part pressure
FCO2 = Fractionated co2
K = constant

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16
Q

Alveolar vent = (V(CO2) / P(CO2)) x K

17
Q

alveolar Vent and PCO2 are inversely proportional

A

dbl alveolar vent = half PCO2

Half Alveolar vent = dbl PCO2

18
Q

CSA increases as we get lower into the alveolar

19
Q

ratio of ventilation to blood flow

20
Q

concentration of dry air and partial pressure

A

FO2 = 0.21 (21%)
Baro Pressure = 760 mmHg

PO2 = 0.21 x 760
= 160 mmHg

21
Q

Effect of water vapor and partial pressure

A

Baro Pressure 760 mmHg
37C = Ph2o = 47 mmHg
Pdry = 760 - 47 = 713mmHg

PO2 = 0.21 x 713
= 150 mmHg

22
Q

If water vapor is 100C

A

Water vapor
PO2 = 760 mmHg

temp when water boils

23
Q

partial pressure of air in water

24
Q

air O2 = 21ml/dl
water O2 = .45 ml/dl

A

solubility of o2 in h20
= 0.45 x 150 mmHg
= 0.003 ml/dl/mmHg

25
Q

solubility = 0.003 ml/dl/mmHg
PO2 art = 100mmHg

A

0.003 x 100 mmHg
= 0.3ml/dl = 3ml/L (O2)

CO = 30L/min
Max O2 avail = 90ml/min
O2 req = 3000ml/min

26
Q

HGB dissociation curve

A

Art Blood 100 PO2,mmHG / 100 O2 sat

Venous blood 40 PO2 mmHg / 75 O2 sat

P50 27 PO2 mmHg / 50 O2 sat

27
Q

Total O2 concentration of arterial blood

A

1.39 ml/o2 / 1g hgb / %sat/100 + 0.003 x po2

ex
1.39 x 15 x .97 + 0.003 (100)
= 20.5 ml/dl

28
Q

What shifts the O2 curve to the right?

A

increase in
CO2, H+, 2,3 DPG, Temp.

29
Q

How much more affinity of O2 is CO (carbon monoxide)?

30
Q

What are the 3 forms of CO2 in the blood?

A

dissolved
bicarb
carbamino compounds

31
Q

solubility of o2 in blood

solubility of CO2 in blood

A

0.003 ml/dl

0.067 ml/dl (24x more)