Jeff's cards Flashcards
Alexander the Great refused to let his troops eat fish due to this toxin;
Most common fish food poisoning in tropical coastal regions
Ciguatera toxin
Sxs: GI –> neuro
Fish + histamine
Sombroid
Red tide + fish toxin
Saxitoxin
Pufferfish (fugu) toxin
Tetrodotoxin
Cyanide toxicity Tx
Inahled?
IV?
Amyl nitrite
Sodium thiosulfate
TCA toxicity
Na bicarb
Bitter almond
Garlic
Cyanide
Arsenic
methgb toxicity Tx
methylene blue
ethylene glycol toxicity Tx
ethanol or fomepizole
organophosphate toxicity Tx
atropine; pralidoxime
BZO toxicity Tx
flumazenil
osmolar gap & ketosis w/o sig met acidosis
isopropyl alcohol
pt on a beta blocker goes into anaphylactic. shock refractory to epi
glucagon
lactic acidosis, AMS, on nitroprusside drip
cyanide
decompression sickness
accumulation of nitrogen gas
nomogram for acetaminophen toxicity
modified Rumack-Matthew nomogram
salicylate toxicity Tx
alkalinization of urine
carbon monoxide poisoning with coma
hyperbaric chamber
electrolyte abnormality a/w MDMA (ectasy)
hyponatremia
antivenom rxn (1-2 weeks)
serum sickness
cholinergic toxicity
SLUDGE: salivation, lacrimation, urination, diarrhea, gastric emptying
BBB: bronchospasm, bradycardia, bronchorrhea
2 alcohols that cause high AG
methanol, ethanol
alcohol that doesn’t cause high AG. Why?
isopropyl alcohol (converted to acetone–neutral compound)
lithium toxicity Tx
HD
anticholinergic toxicity
red as a beet, dry as a bone, mad as a hatter, blind as a bat
NMJ disease, improves with use
Lambert Eaton
yellow tint in CSF
xanthochromia
prion disease, PNG
Kuru
1 inherited peripheral neuropathy
Charcot-Marie-Tooth
impaired short term memory with confabulation, normal cognition
Korsakoff
ipsilateral weakness, contralateral loss of pain/temp
Brown-Sequard
wernickes triad
nystagmus
encephalopathy
ataxia
Charcot’s triad (for MS)
scanning speech, intention tremor, nystagmus
Stroke like symptoms following seizure
Todd’s paralysis
miners of this element get PD
manganese
test for NPH
Miller-Fischer test (remove 30 cc CSF and walk again)
plexus in achalasia
Auerbachs
plexus in Hirshsprungs
Meyers
protein found in Lewy Bodies
synuclein
Cushings reflex (triad)
HTN, bradycardia, irregular respirations
rapidly progressive dementia with startle myoclonus. CSF protein
CJD.
14-3-3
acute memory loss lasting minutes w/o LOC
transient global amnesia
auditory symptoms a/w Bell’s palsy
hyperacusis
Tx for spasmodic torticollis (cervical dystonia)
Botox injections
Parkinsons + dysautonomia + ataxia + corticospinal tract signs
Multiple system atrophy
pupil with consenual but not direct response to light. eponym
afferent pupillary defect (Marcus Gunn pupil)
1 malignant eye tumor
melanoma
1 presentation of MS
optic neuritis
corkscrew conjunctival vessels
sickle cell disease
glaucoma dx criteria (3)
progressive loss of peripheral vision, high IOP, abnormal cup/disc ratio
pseudotumor cerebri Tx
acetazolamide
Daily spiking fevers (quotidian), arthritis and an evenescent “salmon-colored” rash
Adult stills disease
Pain at at the elbow is reproduced with the extension of the wrist against resistance
Lateral epicondylitis (Tennis elbow)
RA index finger abnormality
boutonniere deformity (PIP hyperflexion with DIP hyperextension)
proximal muslce weakness and elevated CK levels in a patient on chronic treatment for gout
colchicine myopathy
seronegative spondyloarthropathies
Reactive arthritis, IBD-associated, Psoriatic, Ankylosing spondylitis
TNF alpha inhibitors (3)
Infliximab
Ertanercept
Adalimumab
Felty’s syndrome (3)
neutropenia, splenomegaly, RA
stridor and hoarseness in a patient with RA is a signal for involvement of this joint. Tx?
Cricoarythenoid synovitis (steroids!)
2 large vessel vasculitidies
Giant cell arteritis, Takayusu arteritis
active Hep B and vasculitis
PAN (polyarteritis nodosa)
low complement levels in these 2 vasculitidies
Cryoglobulinemia, SLE vasculitis
antibody associated with the absence of interstitial lung disease in patients with scleroderma
anti-centromere
autoantibodies associated with interstitial lung disease, arthritis, and a hyperkeratotic rash on the hands
Antihistidyl-tRNA synthetase
Test for lacrimal function in patients with dry eyes
schirmer test
pain localized to the distal radius and a positive Finkelstein’s test
De Quervain’s tenosynovitis
Most common extra-articular manifestation of ankylosing spondylitis
acute anterior uveitis
candlewax appearance on back x-ray
DISH (diffuse idiopathic skeletal hyperostosis)