Jaundice

Question 1

What are the three classifications of the cause of jaundice?

Answer 1

a. Increased production: haemolysis
b. Decreased excretion: Gilberts, Dubin-Johnson, hepatitis
c. Obstruction: extrahepatitic cholestasis (elevated conjugated bilirubin); intrahepatic cholestasis (no jaundice, no increase in bilirubin)

Question 2

What are the three classifications of the cause of jaundice?

Answer 2

a. Increased production: haemolysis
b. Decreased excretion: Gilberts, Dubin-Johnson, hepatitis
c. Obstruction: extrahepatitic cholestasis (elevated conjugated bilirubin); intrahepatic cholestasis (no jaundice, no increase in bilirubin)

Question 3

What are the three classifications of the cause of jaundice?

Answer 3

Increased production
Decreased excretion
Obstruction

Question 4

Enzyme profile for extra hepatic v intra hepatic biliary obstruction?

Answer 4

Extra hepatic: GGT+++ and ALP ++++ (larger volume of biliary tree obstructed therefore greater damage)
Intra hepatic: GGT + and ALP +