Jaundice Flashcards
What is the definition of jaundice?
What is the normal level of bilirubin in the body? What level causes clinical jaundice?
Explain the production and excretion of bile.
Which is fat soluble and which is water soluble?
Unconjugated or conjugated bilirubin
Differentiate between pre, intra and post hepatic causes of jaundice in terms of LFTs.
|PRE
serum bilirubin only
|INTRA
serum bilirubin, AST, ALT, Lactate, gamma GT
|POST
Alk phos (significant increase), gamma GT (significant increase), Serum bilirubin
What are the causes of UNCONJUGATED jaundice?
What are the causes of CONJUGATED jaundice?
Explain the pathophysiology and give causes of prehepatic jaundice.
Explain the pathophysiology and give causes of hepatocellular jaundice.
Explain the pathophysiology and give causes of post-hepatic jaundice. Include the symptoms expected.
Compare Gilbert’s Syndrome and Crigler Najjar Syndrome.
What question would you ask in a history on jaundice?
What is courvoisier’s law?
What exam findings will you be looking for in a case of jaundice?