January Flashcards
8-4 weeks
Secondary prevention following TIA
75mg Clopidogrel
What medications should a patient take prior to PCI?
First, a loading dose of aspirin 300mg should be given for the STEMI
For those having primary PCI, NICE recommend adding prasugrel if the patient is not already taking an oral anticoagulant.
Nail changes seen in iron deficiency anaemia?
Kolionychia (spoon shaped nails)
Uraemia with what symptoms in AKI is an indication for dialysis?
Uraemia + encephalopathy or pericarditis is an indication for dialysis
Signs of anaemia + positive coombs test (direct antiglobulin test) indicates what?
Autoimmune haemolytic anaemia
Autoimmune haemolytic anaemia tx
Corticosteroids 1st line
- reduces the number of circulating antibodies.
C peptide levels in Type 1 vs Type 2 diabetes
Type 1 = C peptide low / undetectable due to deficiency in insulin
Type 2 = C peptide raised
Brown-green nipple discharge is most commonly associated with…
Duct ectasia
What is a small and medium vessel vasculitis that is strongly associated with smoking.
Features
extremity ischaemia
intermittent claudication
ischaemic ulcers
superficial thrombophlebitis
Raynaud’s phenomenon
Buerger’s disease (also known as thromboangiitis obliterans)
When can you watch and wait with a kidney stone?
Watchful waiting is incorrect. NICE guidelines suggest that renal stones with dimensions of 5mm or less should initially be managed using a watchful waiting approach, making sure that the patient remains well-hydrated, has an appropriate prescription of analgesia and is safety-netted for the signs and symptoms of infection.
Kidney stone 8mmx5mm treatment?
Shockwave lithotripsy and tamsulosin.
Kidney stone size 21mm tx?
Percutaneous nephrolithotomy involves a small incision in the back and the insertion of a needle into the kidney using fluoroscopy or ultrasound. The urinary tract is then dilated and the stone is fragmented using lasers or lithotripsy devices. This approach is used for renal stones larger than 20 mm, including staghorn stones, as it is the most invasive of the options and should be reserved for cases when minimally invasive approaches would not be enough.
Kidney stone size 14mm tx?
Ureteroscopy is a minimally invasive procedure which involves a ureteroscope being passed through the urethra and bladder to reach the stone in the ureter or kidney. Stones can then be fragmented with lasers or removed intact. This approach is indicated by NICE guidelines for renal and ureteric stones between 10 and 20 mm in size.
Hepatitis E most common method of transmission
Hepatitis E is spread by the faecal-oral route and is most commonly spread by undercooked pork
Angina management
(1st and 2nd line)
- Verapamil + GTN
- Beta blockers + GTN
- Isosorbide mononitrate + GTN
Chest drain indications for pneumothoax
Haemodynamic compromise (suggesting a tension pneumothorax)
Significant hypoxia
Bilateral pneumothorax
Underlying lung disease
≥ 50 years of age with significant smoking history
Haemothorax
Treatment of vestibular neuronitis
Prochlorperazine may be useful in the acute phase of vestibular neuronitis, but should be stopped after a few days as it delays recovery by interfering with central compensatory mechanisms
Most common causes of small bowel obstruction
Adhesions (any previous surgery)
Hernia
Infective endocarditis in IVDU typically affects what valve?
Tricuspid valve
What muscle relaxant is the first choice for rapid sequence induction for intubation
Suxamethonium is the muscle relaxant of choice for rapid sequence induction for intubation.
What antibodies are seen in primary biliary cholangitis?
- Anti-mitochondrial antibodies (AMA) M2 subtypeare present in 98% of patients and are highly specific
- Smooth muscle antibodies in 30% of patients
- Raised serum IgM
Management of primary biliary cholangitis:
(3 medical treatments and 1 surgical)
- First-line:Ursodeoxycholic acid
- slows disease progression and improves symptoms
- Pruritus:Cholestyramine
- Fat-soluble vitamin supplementation
- Liver transplantation
- e.g. if bilirubin > 100 (PBC is a major indication)
- Recurrence in graft can occur but is not usually a problem
Chlamydia treatment if pregnant?
Azithromycin, erythromycin or amoxicillin
Retro-orbital headache, fever, rash, bone break pain and muscle ache, thrombocytopenia in a returning traveller - treatment?
Dengue fever
- fluid resus and blood transfusion - no antivirals are available.