James Bloomer Psych SBAs Flashcards

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1
Q

The MMSE assesses the following aspects of cognitive function EXCEPT:

a) Orientation
b) Long term memory
c) Registration and recall
d) Calculation
e) Language

A

b) Long term memory

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2
Q

You are working in general practice. Peter Townsend is a 32 year old man who has been treated for schizophrenia for the last 10 years. He wishes to discuss some symptoms that he thinks are related to his medication.
Which of the following is an example of extrapyramidal side effects of antipsychotic medication?

a) Mannerisms
b) Akathisia
c) Stereotypies
d) Compulsions
e) Tics

A

b) Akathisia

Akathisia is usually a relatively early side effect of antipsychotics, and is a subjective sense of restlessness. Patients feel unable to sit still, and may pace relentlessly to relieve this unpleasant feeling. Akathisia is associated with an increased risk of suicide. The other options are examples of repeated movements, but are not caused by antipsychotic use. Antipsychotics are sometimes used to treat tics.

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3
Q

During an assessment of a 40 year old woman in accident and emergency, you note that she seemingly becomes “stuck” on one answer, repeating it inappropriately in answer to a series of questions. You correctly recognize this as perseveration.
Which of the following is MOST likely to cause perseveration?

a) Mood disorders
b) Personality disorders
c) Substance misuse
d) Organic disorder
e) Schizophrenia

A

d) Organic disorder

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4
Q

Rufus Martinsdale is a 21 year old man with a diagnosis of schizophrenia. He experiences hallucinations and delusions.
Rufus is most likely to experience hallucinations in which of the following modalities?

a) Visual
b) Olfactory
c) Tactile
d) Gustatory
e) Auditory

A

e) Auditory

Most common type in schizophrenia

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5
Q

Cindy Goggins lives in London and is well known to psychiatric services with a diagnosis of paranoid schizophrenia. She has relapsed, following non-concordance with her olanzapine, and is now presenting with auditory hallucinations and persecutory delusions, in a manner almost identical to that of her previous relapse. Cindy has refused to engage with her Care Coordinator for the past three weeks, and her family report she is not eating and drinking, since she believes terrorists have spiked her food with ricin. The Community Mental Health Team are organizing a Mental Health Act Assessment to allow Cindy to be admitted to psychiatric hospital for treatment of her schizophrenia.
Which section of the Mental Health Act is most appropriate in this situation?

a) 2
b) 3
c) 5
d) 12
e) 136

A

b) 3

Section 3 of the Mental Health Act enables admission for treatment for a period of up to 6 months. If Cindy was an unknown patient, had presented differently to usual, or her diagnosis was in doubt for any reason, a Section 2 should be used, to admit her for assessment.

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6
Q

Dimitrios Bekas is a 22 year old man, who was admitted informally to a psychiatric ward following a suicide attempt. The nursing staff have contacted you, as the on-call doctor, because Mr Bekas has become agitated and wishes to leave the ward. You assess Mr Bekas, and are concerned that he is very distressed and remains at high risk of self-harm if he leaves hospital tonight. You inform the registrar on-call, and are advised to place Mr Bekas under Section 5(2) of the Mental Health Act.
How long can Mr Bekas be held in hospital under Section 5(2)?

a) 48 hours
b) 72 hours
c) 1 week
d) 1 month
e) 3 months

A

b) 72 hours

Section 5(2) allows a patient already on an inpatient ward to be detained for a maximum of 72 hours. It only requires the recommendation of 1 doctor, who does not need specialist Mental Health Act training. Only in extreme circumstances should a patient be detained under a Section 5(2) for the full 72 hours. Best practice is that the patient should receive a formal Mental Health Act assessment as soon as possible to decide whether they can go home or whether they should remain in hospital for assessment (Section 2) or treatment (section 3).

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7
Q

Mrs Bailey is an 82 year old woman, who lost her husband 3 months ago. She is admitted to Accident and Emergency with chest pain and a heart attack is diagnosed. Her condition and treatment options are explained to her, but she refuses treatment and wishes to return home. Her daughter, Emma, is her legal next of kin. Emma explains that her mother has ‘given up’, and hasn’t been herself since Mr Bailey’s death. Emma tearfully asks you to treat her mother.

a) She is likely to be suffering an abnormal grief reaction.
b) In accordance with the Mental Health Act, her medical condition can be treated under Section 3.
c) The incidence of myocardial infarction is increased in those who have recently suffered the loss of their spouse.
d) She is suffering severe depression and lacks the capacity to make decisions about her medical care.
e) An elderly patient can be treated at the behest of their next of kin if it is judged they lack the capacity to consent to treatment.

A

c) The incidence of myocardial infarction is increased in those who have recently suffered the loss of their spouse.

Abnormal grief reactions are not diagnosed unless there is something unusual or severe about the grief process. There is nothing here to suggest that Mrs Bailey’s reaction is abnormal, and she should not be expected to be “back to normal” after only 3 months since her loss. Medical conditions are not routinely treated under the Mental Health Act. There is insufficient information here to decide whether Mrs Bailey is depressed or lacks capacity to make decisions about her medical care. Even if she is found to lack capacity, her next of kin cannot consent on her behalf: no-one can give consent for treatment on behalf of an adult. Mrs Bailey’s capacity must be assessed urgently.

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8
Q

You are a student attached to a psychiatric firm. You are preparing to interview a patient.
Which of the following is TRUE?

a) Interviewing in pairs is intimidating to the patient and should be avoided as far as possible.
b) Formal dress is important since it implies respect for your patient; men should wear ties.
c) It is important to arrange the seating in the interview room prior to the interview.
d) Whilst patients are intoxicated their symptoms are easier to elicit due to disinhibition; it is often a good time to conduct an initial interview.
e) Violent outbursts often occur ‘out of the blue’ and are usually impossible to predict.

A

c) It is important to arrange the seating in the interview room prior to the interview.

Taking time to prepare a room prior to an interview can improve safety, allowing you to arrange the seating so that you can sit nearest the door and alarms. Ties and neck-wear (e.g. scarves or lanyards) can be hazardous if the patient becomes aggressive. Interviewing in pairs increases your personal safety. Interviews should not be conducted while patients are intoxicated with drugs or alcohol: intoxicated patients are more volatile and it is usually not possible to assess their underlying mental state. There are often clear warning signs of increasing tension prior to a violent outburst; be alert to early warning signs.

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9
Q

Mrs Jane Hopkins is a 27 year old designer who has come to her GP due to feeling sad and progressively more tired over the last month. She also has trouble getting to sleep and wakes up much earlier than she used to. She doesn’t enjoy her work anymore.
Which investigation is NOT considered routine when assessing the potential biological causes of this condition?

a) Physical examination
b) Computed tomography (CT)
c) Thyroid function tests (TFT)
d) Full blood count (FBC)
e) Glucose or HbA1c

A

b) Computed tomography (CT)

Feedback:

CT or MRI may however be helpful in ruling out suspected cerebral pathology in a minority of patients. Hypothyroidism, anaemia, and diabetes are common causes of tiredness.

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10
Q

Helen Santos is a 32 year old bank clerk who was diagnosed with depression two weeks ago and started on an antidepressant. She has been brought to A&E by her partner, John, who is very worried about her. He tells you that she seems to have suffered a “personality change” becoming very irritable, loud, and rude over the past week. Her sleep has been poor and this morning John found her cooking breakfast at 4am.
She is very fidgety during the consultation but says that she is enjoying her new job as a fashion designer.
Which of the following is the MOST LIKELY diagnosis:

a) Refractory depression
b) Multiple sclerosis
c) Hyponatraemia
d) Serotonin syndrome
e) Mania

A

e) Mania

Feedback:

Antidepressants can ‘switch’ some people from depression into mania, even without a previous history of mania.

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11
Q

Mrs Santos is started on lithium.
With regards to this treatment, which of the following options is INCORRECT?

a) The therapeutic range of lithium is 0.6 - 1.0mmol/litre.
b) Levels are taken 12 hours post-dose.
c) Lithium blood levels must be checked weekly until the treatment is stopped.
d) It may cause hypothyroidism and renal impairment.
e) Toxicity may be triggered by dietary changes or vomiting.

A

c) Lithium blood levels must be checked weekly until the treatment is stopped.

Feedback:

Lithium levels need to be checked weekly until therapeutic and stable. Then three monthly checkups together with U&Es and TFTs are sufficient.

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12
Q

Mrs Viola Jones lost her husband Harry four months ago. Initially she felt she was in a state of shock, and “everything passed in a slow blur”. She missed Harry dreadfully, and says that she cried for hours every day for the first few weeks. Now, although she isn’t crying for hours, she still spends much of her time thinking about Harry and the 37 years they spent together. She is easily moved to tears by little things that remind her of him.
She doesn’t seem to want to cook for herself anymore and instead buys sandwiches at the local shop. Although she seems to have regained the weight she lost in the first month, eating in this way is still very out of character for her. It would have been Harry’s birthday last week, and while the rest of the family got together to remember Harry, Viola “wanted to be alone” and seemed more tearful than ever.
Which of the following BEST describes Viola’s current situation?

a) Bereavement
b) Adjustment disorder
c) Prolonged bereavement
d) Depression
e) Pseudodementia

A

a) Bereavement

Feedback:

She is progressing through the normal stages of grief, which include numbness, pining, depression, recovery. There is evidence that she is moving forward, e.g. though she is still preoccupied by the loss, she is now intermittently - rather than constantly - tearful. A major anniversary is expected to bring on ‘the pangs of grief’ and it can be helpful to let patients and their relatives know this, to normalize it. Although Viola is not cooking for herself, she is still eating and caring for herself. It can be very hard to cook for ‘one’ after 37 years of cooking for ‘two’.

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13
Q

Six months later, Mrs Jones is still very low in mood when you pay her a home visit at her son’s request. She speaks slowly and quietly. She is tearful and avoids eye contact. You only have 30 minutes before the next house call.
What should you do when interviewing this patient?

a) Try to distract her to stop her from crying.
b) Speak louder to get her attention.
c) Show empathy by explaining that you know how she feels.
d) Give extra time for her to answer your questions.
e) Offer her a prescription for an antidepressant and arrange to review her in a week.

A

d) Give extra time for her to answer your questions.

Feedback:

All other options may make her close down and lose confidence in you.

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14
Q

Mr Reed is a 58 year old man with a history of depression. He presents to A&E following an overdose of 16 paracetamol, which he believed to be lethal. His wife came home from work at the usual time, and found him slumped on the couch in the lounge. She was able to tell you that that the front door was on the latch, and there was a suicide note beside him, which said that he was sorry, but couldn’t go on anymore. Mr Reed says he bought the paracetamol a week ago “just in case”, and is glad that he was found by his wife.
Which of the following REDUCE the likelihood that this was a serious attempt at suicide?

a) Took only 16 paracetamol.
b) Few precautions to avoid being found.
c) Left suicide note.
d) Purchased the paracetamol only a week in advance.
e) Isolation at the time of the act.

A

b) Few precautions to avoid being found.

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15
Q

Mr Reed now wants to self-discharge, though he has not yet received investigations or treatment for his overdose.
What will you do now?

a) Check paracetamol levels immediately.
b) Arrange compulsory admission to hospital under Section 2 of the Mental Health Act.
c) Assess his capacity to self-discharge.
d) Give naloxone.
e) Give N-acetyl cysteine.

A

c) Assess his capacity to self-discharge.

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16
Q

Xiu Mei is 16 and has been cutting herself for the past 3 years. She is worried about the longer term scarring and wants to cut down her self-harm.
Which of the following is a useful strategy to reduce the drive to self-harm?

a) Staying in a private place in order to calm down.
b) Looking at pictures of self-harm instead of performing it.
c) Avoiding talking to friends and family.
d) Using a washable red pen to mark the skin instead of cutting it.
e) Drinking a small amount of alcohol to relax.

A

d) Using a washable red pen to mark the skin instead of cutting it.

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17
Q

Which of the following is true of the epidemiology of suicide?

a) Men are more likely to attempt suicide than women.
b) Globally the suicide rate is decreasing as a result of reduced access to means.
c) It is the second largest cause of death in men aged 15 to 24.
d) 1 in 1000 deaths are suicides.
e) Women tend to use more violent methods than men

A

c) It is the second largest cause of death in men aged 15 to 24.

Feedback:

Road traffic accidents are the leading cause of death in this age group.

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18
Q

A 21 year old man is brought into A&E by his mother. He reports that MI5 agents are telling him to kill himself to avoid being tortured for information. He was recently diagnosed with schizophrenia following eight months of gradually worsening auditory hallucinations and the delusion that he was an undercover spy. His illness caused him to drop out of university where he studied ecology, though he hopes to return to complete his studies in a year’s time. He has never believed himself to be ill and has been poorly compliant with his medication.
In schizophrenia, which of the following REDUCES his risk of suicide?

a) Youth
b) Early stages of illness
c) Command hallucinations
d) Good premorbid functioning
e) Hope

A

e) Hope

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19
Q

Which of the following is true regarding the aetiological factors in schizophrenia?

a) The child of a person with schizophrenia has a 22% lifetime risk of developing schizophrenia.
b) Tetrahydrocannabinol has been shown to protect against the risk of developing schizophrenia, when used regularly by teenagers.
c) The incidence of schizophrenia is doubled in urban areas, compared with rural areas.
d) Summer birth is associated with an increased risk of schizophrenia.
e) Schizophrenia has a similar incidence across all social classes.

A

c) The incidence of schizophrenia is doubled in urban areas, compared with rural areas.

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20
Q

Which of the following is NOT one of Schneider’s first rank symptoms of schizophrenia?

a) Somatic passivity
b) Persecutory delusions
c) Outside agencies causing the person’s actions
d) Hallucinations of a running commentary on the person’s actions
e) Delusional perception

A

b) Persecutory delusions

Feedback:

The delusions that count as “first rank symptoms” are: delusional perception, thought insertion, thought withdrawal, thought broadcasting, passivity phenomena. Other first rank symptoms are hallucinations: thought echo; voices discussing or arguing about the patient; voices giving a running commentary on the patient’s actions.

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21
Q

A GP is called to the house of a 72 year old man after his sister expressed concerns that she hadn’t been able to contact him for 3 months. His house was very untidy and unclean. He had a blank expression, took a long time to answer questions, and said very little, speaking slowly with a monotonous tone.
Which of the following is LEAST likely to be the cause of these symptoms?

a) Cognitive impairment
b) Persistent delusional disorder
c) Parkinson’s disease
d) Antipsychotic medication side effects
e) Depression

A

b) Persistent delusional disorder

Feedback:

Although persistent delusional disorder might result in neglect of this man’s house (e.g. a belief that he was being spied upon might distract him from housework), it would not be associated with the blank facial expression and speech abnormalities. Cognitive impairment (e.g. delirium or dementia), Parkinson’s disease, parkinsonism secondary to antipsychotics, and depression could each cause the presentation.

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22
Q

Which of the following is TRUE of atypical antipsychotics?

a) They block 5-HT2 receptors.
b) They carry a higher risk of tardive dyskinesia than typical antipsychotics.
c) They block presynaptic D2 receptors.
d) They are the second line choice in schizophrenia.
e) Hyperprolactinaemia is the major problem with this drug group.

A

a) They block 5-HT2 receptors

Feedback:

Note that this is in addition to their antagonism of post-synaptic D2 receptors.

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23
Q

Which of the following is predictive of poor prognosis in schizophrenia?

a) Late onset
b) Abrupt onset
c) Short duration of untreated psychosis
d) Concordance with medication
e) Substance misuse

A

e) Substance misuse

Feedback:

The other answers are associated with a better prognosis in schizophrenia.

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24
Q

A young male, smelling of alcohol, is brought in to A&E by the police. He is verbally abusive to the staff, especially the nurse in charge, who asks you to see him straight away.
Which of the options below is the MOST APPROPRIATE first step in assessing this patient?

a) Prescribe some sedatives to calm the patient down.
b) Order a urine drug screen (UDS).
c) Ask the patient how many drinks he has had and calculate his weekly units.
d) Review the medical notes.
e) Give him an injection of thiamine to avoid delirium tremens.

A

d) Review the medical notes.

Feedback:

Reviewing the notes gives you the opportunity to look for evidence of substance misuse and past psychiatric history; they may also note risk issues. Diving straight into an assessment without a brief understanding of the situation is hazardous.

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25
Q

Having interviewed your intoxicated patient, you decide to request a urine drug screen (UDS).
Which of the substances below is NOT usually detected by a UDS?

a) Cannabis
b) LSD
c) Amphetamine
d) Heroin
e) Cocaine

A

b) LSD

Feedback:

LSD is rapidly removed by the body and very difficult to detect in the urine.

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26
Q

A confused, middle-aged woman, with a long-standing history of alcohol misuse is brought into A&E by her brother. He tells you that she’s been shaky and sweaty for the last two days, and has been terrified of dogs attacking her in her bedroom. He states that there are no dogs in the house.
Which of the options below is MOST LIKELY to have triggered her symptoms?

a) Subdural haematoma
b) Sepsis
c) Benzodiazepine overdose
d) Alcohol intoxication
e) Abstinence from alcohol

A

e) Abstinence from alcohol

Feedback:

The patient presents with physical signs of alcohol withdrawal (shaking, sweating) together with hallucinations, confusion, and affective changes. It is likely that she has been abstinent (or markedly reduced her alcohol intake) in the past 2-3 days. Her presentation strongly suggests delirium tremens and she should promptly receive benzodiazepines and parenteral thiamine. Though hallucinations can occur while drinking alcohol (alcoholic hallucinosis), these tend to be auditory hallucinations with a persecutory or derogatory content, and are experienced in clear consciousness.

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27
Q

Which of the following options are you LEAST likely to elicit on examination of a patient with Wernicke’s encephalopathy?

a) Confusion
b) Irreversible anterograde amnesia
c) Nystagmus
d) Ataxia
e) Ophthalmoplegia

A

b) Irreversible anterograde amnesia

Feedback:

Irreversible anterograde amnesia is characteristic of the Korsakoff syndrome (or the Korsakoff component of Wernicke-Korsakoff syndrome). In an acute confusional state such as Wernicke’s encephalopathy it is not possible to assess whether a patient has a true anterograde amnesia, and certainly not possible to predict whether it will be reversible.

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28
Q

A 32 year old man is suffering from heroin withdrawal.
Which of the symptoms below is LEAST likely to happen during this process?

a) Cramps and aches
b) Death
c) Nausea and vomiting
d) Lacrimation
e) Insomnia

A

b) Death

Feedback:

Opiate withdrawal may be very unpleasant but, in adults, does not directly cause death.

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29
Q

You are a medical student in urology clinic. A 72 year old man has been referred by his GP due to his increasing symptoms of urinary incontinence. You assist him into the room as he is very unsteady on his feet, with a shuffling gait. He is accompanied by his wife, who gives the history as he has become “very forgetful” recently.
He is referred for a head CT scan. What would you expect this to show?

a) Multiple small areas of ischaemia
b) Dilated ventricles
c) Caudate nucleus atrophy
d) Normal CT
e) Global atrophy

A

b) Dilated ventricles

Feedback:

The clinical triad of urinary incontinence, confusion, and unsteady gait is the clue to the diagnosis: normal pressure hydrocephalus. CT scan shows dilated ventricles.

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30
Q

You confirm the diagnosis of normal pressure hydrocephalus.
What would be the most appropriate treatment?

a) Acetylcholinesterase inhibitors
b) Levodopa
c) Diuretics
d) Ventriculo-atrial shunt
e) No specific treatment is yet available

A

d) Ventriculo-atrial shunt

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31
Q

A 58 year old man, known to be HIV positive, is followed up in clinic. The previous entry in the notes reports him to have been very withdrawn at his last attendance. His friend reports that he has deteriorated, with notable memory impairment, apathy, and poor coordination.
Which of the following is NOT true regarding this form of dementia?

a) Incidence has halved since the introduction of HAART
b) It affects 10% of HIV patients
c) Prevalence has risen since the introduction of HAART
d) It is characterized by neurological features including seizures
e) MRI characteristically shows global atrophy and diffuse grey matter signal changes

A

e) MRI characteristically shows global atrophy and diffuse grey matter signal changes

Feedback:

MRI may show atrophy and diffuse white matter signal changes.

32
Q

It is 5 o’clock in the morning and you are asked to see an 87 year old lady who was admitted earlier in the night with a fractured neck of femur following a fall. Physical examination was otherwise normal. She has a 3 year history of gradually increasing memory impairment. You arrive at the ward to find her shouting for her husband who passed away last year. You note that she is on galantamine.
What is the most appropriate immediate management of this patient?

a) Prescribe a small dose of lorazepam (e.g. 0.5mg) to reduce her distress and make it safer to assess her.
b) Physical examination, urine dipstick, blood glucose and chest X-ray
c) Increase the dose of galantamine
d) Commence broad-spectrum antibiotics to treat possible infection.
e) Move her to a side room to prevent further disturbance.

A

b) Physical examination, urine dipstick, blood glucose and chest X-ray

Feedback:

Without further history, it’s not possible to know whether this woman usually presents in this way (even though she has a history of memory problems). Dementia can look like this, though it is likely that her distress relates either to her change of environment, or to a superimposed delirium state, secondary to infection. Try to hold off medications until you know the underlying cause, so that you can fully assess your patient, and not cause further problems through unnecessary drug side effects e.g. sedation, antibiotic resistance. A side room may increase her confusion and distress, since there may be no clues to help her orientate herself. Additionally, her needs are more likely to be overlooked by nursing staff in a side room - despite the fact that her distress may indicate that she is a seriously ill patient.

33
Q

A 63 year old lady who was previously fit and well suffers an ischaemic stroke and is left with some left-sided weakness. She is able to mobilize with a frame and carry out most of her ADLs independently. There is no evidence of cognitive impairment and she has no past psychiatric history.
Which of the following disorders is most likely in the year following the stroke?

a) Hypomania
b) Agoraphobia
c) Depression
d) Social phobia
e) Alcohol dependency

A

c) Depression

34
Q

A 42 year old woman attends the GP practice. Her husband has just been diagnosed with Huntington’s chorea aged 40, and she wants some advice and information, since they have a son and she is concerned that he may have inherited the disorder.
Which of the following statements is TRUE?

a) You are unable to offer this lady any information as you have a duty of confidentiality to her husband
b) Her son has a 25% chance of inheriting the disorder
c) If her son does have Huntington’s disease, he is likely to become symptomatic at a younger age than his father
d) Although there is no cure, levodopa may temporarily alleviate symptoms
e) Genetic testing is not available

A

c) If her son does have Huntington’s disease, he is likely to become symptomatic at a younger age than his father

Feedback:

Onset is usually in early middle age, though longer CAG repeats cause earlier and more severe presentations; lengthening occurs with each inheritance, so that onset is younger in subsequent generations (“anticipation”).

35
Q

A 72 year old woman experiences visual hallucinations and becomes very disruptive while on the ward. The on-call doctor prescribes a new medication. A few days later, the woman deteriorates, becoming feverish, with muscle rigidity, and worsening confusion.
What is the MOST likely cause of this presentation?

a) Serotonin syndrome in response to antidepressant
b) Neuroleptic sensitivity, due to addition of antipsychotic
c) Phenelzine (MAOI) drug interaction
d) Delirium secondary to infection
e) Lithium toxicity

A

b) Neuroleptic sensitivity, due to addition of antipsychotic

Feedback:

This is a potentially fatal problem encountered in Dementia with Lewy Bodies (DLB). It resembles Neuroleptic Malignant Syndrome in many ways. Always think carefully before prescribing antipsychotics for “delirium” - especially in elderly patients with visual hallucinations - DLB can resemble delirium. Symptoms of DLB include: fluctuating confusion; vivid visual hallucinations (often of people or animals); parkinsonism; repeated falls, syncope; transient losses of consciousness. Short-term memory is often less affected than in Alzheimer’s disease or vascular dementia.

36
Q

A 72 year old lady presents to A&E with a fractured neck of femur. She will require an operation. She is noted to have some memory impairment and you are asked to assess her capacity to consent to this procedure.
Which of the following will mean she lacks capacity?

a) MMSE score of 12/30
b) Able to understand that she would benefit from an operation but unable to understand the risks involved
c) Deafness and severe dysarthria causing incomprehensible speech
d) Inability to recollect that she was going to have the operation at the next ward round, four days later.
e) Longstanding severe visual impairment and profound deafness

A

b) Able to understand that she would benefit from an operation but unable to understand the risks involved

Feedback:

A low MMSE score would be suggestive of possible capacity problems, but is not sufficient to assess someone as lacking capacity. Communication problems such as deafness, dysarthria, or visual problems are challenging - but it is your responsibility to try everything you can to overcome them (e.g. simply writing questions and answers down may suffice in deafness / dysarthria). Being unable to remember the conversation at the next ward round is worrying, but if your patient was able to retain the information long enough to weigh it and make the initial decision, she still has capacity.

37
Q

Your consultant asks you to see a 71 year old woman whose husband reports that she no longer recognizes their grandchildren, despite clearly being able to see them, and even being able to recite their names.
Which of the following terms will you use to describe this symptom when presenting her to your consultant?

a) Amnesia
b) Aphasia
c) Agnosia
d) Apraxia
e) Fluctuating consciousness

A

c) Agnosia

Feedback:

Agnosia is the inability to recognize a sensory stimulus despite normal peripheral sensation - in this case, visual agnosia. If she has specific problems with recognising faces, you would call this prosopagnosia.

38
Q

Which of the following is true of depression in old age?

a) 15% of older people in hospital are depressed
b) Selective serotonin reuptake inhibitors are the first line medication
c) There is often a stronger emphasis on cognitive than physical symptoms compared with younger patients
d) The sundowning effect is seen in depressed patients with diurnal variation of mood
e) Pseudodementia does not place people at increased risk of developing later dementia

A

b) Selective serotonin reuptake inhibitors are the first line medication

39
Q

β amyloid precursor protein (APP) is involved in the aetiology of Alzheimer’s Disease.
Which of the following is TRUE of the APP gene?

a) It is located on chromosome 14
b) Mutations are associated with an increased risk of late onset Alzheimer’s disease
c) Mutations are inherited in an autosomal recessive fashion
d) People with Down syndrome possess an extra copy of this gene, and are at increased risk of Alzheimer’s disease
e) Mutations decrease the risk of Alzheimer’s disease

A

d) People with Down syndrome possess an extra copy of this gene, and are at increased risk of Alzheimer’s disease

40
Q

You are working in general practice. Samantha, a 17 year old girl, comes to see you complaining that she is feeling on edge.
Which of the following are symptoms of anxiety?

a) Irritability
b) Depersonalisation
c) Tinnitus
d) Parasthesiae
e) All of the above

A

e) All of the above

41
Q

Jeremy is a 65 year old gentleman who has recently been diagnosed with generalized anxiety disorder. You are working in general practice and he comes to see you, wanting to discuss his condition.
Regarding generalized anxiety disorder, which of the following is TRUE?

a) It is stimulus specific
b) Panic attacks are not a feature of GAD
c) Up to 25% of first degree relatives will also suffer GAD
d) GAD can be diagnosed if symptoms persist for over 1 month
e) Once present, symptoms are constant and unrelenting

A

c) Up to 25% of first degree relatives will also suffer GAD

Feedback:

In GAD, anxiety is not triggered by a specific stimulus, but instead is continuous and generalized (“free-floating). Symptoms can occur at any time, severe cases have panic attacks too. To diagnose GAD, symptoms must be present for at least 6 months, though the intensity may fluctuate.

42
Q

Which of the following has equal prevalence in males and females?

a) Specific phobia
b) PTSD
c) OCD
d) Panic disorder
e) Agoraphobia

A

c) OCD

Feedback:

The others are more common in women than men.

43
Q

Regarding benzodiazepine therapy in anxiety, which of the following is TRUE?

a) They are suitable for medium-term therapy
b) Due to interactions with SSRIs, co-administration should be avoided
c) They act via down-regulation of transmissions through the GABA-A receptors.
d) Cautious use is advocated in those with severe respiratory disease
e) All of the above

A

d) Cautious use is advocated in those with severe respiratory disease

Feedback:

Benzodiazepines can cause respiratory depression and may need to be avoided in those with severe respiratory disease.

44
Q

Which of the following is NOT associated with OCD?

a) Sydenham’s chorea
b) Encephalitis lethargica
c) Phaeochromocytoma
d) Streptococcal throat infection
e) All of the above

A

c) Phaeochromocytoma

Feedback:

The basal ganglia are implicated in OCD, since they are affected by illnesses in which the risk of OCD is increased: Sydenham’s chorea, encephalitis lethargica and Tourette’s syndrome. Anti-basal ganglial antibodies have been demonstrated in people who develop OCD following a streptococcus throat infection. Note that streptococcal infection also causes Sydenham’s chorea.

45
Q

Steve is a 28 year old man who was involved in a road traffic collision yesterday. His cousin who was driving was killed. Since admission to hospital Steve has been aggressive and irritable.
Which of the following is TRUE in an acute stress reaction?

a) It may arise up to 6 months after the event
b) It rarely resolves without treatment
c) Both depersonalisation and derealisation are recognized features
d) Psychological debriefing during an acute stress reaction decreases the risk of developing later PTSD
e) Pharmacological treatment is contraindicated

A

c) Both depersonalisation and derealisation are recognized features

Feedback:

Symptoms can range from irritability and anxiety to aggression or depersonalisation. Patients can seem withdrawn and may have complete amnesia for the triggering event. Debriefing has not been shown to prevent PTSD and may even increase the likelihood of its development.

46
Q

Symptoms of PTSD include all of the following EXCEPT:

a) Flashbacks
b) Avoidance
c) Hypervigilance
d) Hypersomnolence
e) Irritability

A

d) Hypersomnolence

Feedback:

Patients often suffer insomnia and vivid nightmares.

47
Q

Which of the following is TRUE regarding the management of medically unexplained symptoms?

a) CBT is ineffective
b) Repeating investigations often helps to reassure a worried patient
c) A physical examination should be performed
d) Antidepressants should be avoided
e) It should be explained that there is nothing wrong

A

c) A physical examination should be performed

48
Q

Which of the following are true of chronic fatigue disorder?

a) For diagnosis, it must follow a viral infection
b) Other symptoms e.g. aches and pains exclude the diagnosis
c) It is characterized by fatigue after strenuous exercise
d) Extreme fatigue is precipitated by physical or mental exertion
e) Exercise avoidance is important in the management

A

d) Extreme fatigue is precipitated by physical or mental exertion

49
Q

You admit a 58 year old man with a broad Yorkshire accent to a medical ward in a London hospital. He is unable to remember where he came from, his name, or any personal information. You note that he can use the coffee machine without difficulty, and easily orders food from the ward menu. He is flustered but there is no evidence of physical trauma. He remembers your name at the morning ward round, the next day. He is polite, but keeps asking to leave the ward. You eventually track down his identity, and discover that his wife died suddenly, a day before he appeared in your hospital.
What is the most likely diagnosis?

a) Fugue state
b) Malingering
c) Factitious disorder
d) Somatisation disorder
e) Amnesic syndrome

A

a) Fugue state

Feedback:

Patients with a fugue state lose their memory (including personal identity) and wander away from home - sometimes travelling huge distances. Despite their amnesia for personal information, they are usually able to function very well - the coffee machine and food order do not strongly suggest another cause.

50
Q

A 68 year old man whose wife recently had an ischaemic stroke presents with sudden onset of bilateral leg paralysis. On examination he denies sensation to the groin, though twitches slightly as you test pinprick sensation. Reflexes and tone are normal. Motor function is 0/5 throughout, though staff report they have noticed him moving his legs while he is sleeping. CT and nerve conduction studies are normal.
What is the most appropriate management?

a) Rest for 4-6 weeks followed by gradual increase in activity levels
b) Reassure him that symptoms resolve completely in 75% of cases
c) Provide a temporary wheelchair to improve mobility and independence
d) Reassure him that normal function should return quickly
e) Avoid providing further care for his wife, since this will reinforce his symptoms

A

d) Reassure him that normal function should return quickly

Feedback:

This is a conversion disorder.

51
Q

Concerning eating disorders, which of the following statements is TRUE?

a) Anorexia nervosa (AN) is as common as bulimia nervosa (BN)
b) The male: female ratio in anorexia nervosa is 70:30.
c) The incidence of eating disorders in men is decreasing
d) Perfectionism is a trait common to both AN and BN
e) The genetic influence is stronger in BN than in AN

A

d) Perfectionism is a trait common to both AN and BN

Feedback:

Perfectionism and low self-esteem are risk factors for both AN and BN. Theories for AN include the idea that successful weight loss enhances the patient’s sense of achievement, autonomy and perfectionism.

52
Q

Which of the following statements regarding the aetiology of eating disorders is TRUE?

a) Heritability of AN is less than 50%
b) Low self esteem is associated with the development of AN but not BN
c) Approximately 50% of patients with AN have previously suffered with BN
d) Experiences of childhood abuse are more common in AN than in other forms of psychiatric problems
e) Family enmeshment is associated with AN

A

e) Family enmeshment is associated with AN

Feedback:

Enmeshment describes the situation whereby family boundaries are unclear and relationships are over-involved. This can make it difficult for children to develop a sense of autonomy and self-identity.

53
Q

Which of the following statements regarding anorexia nervosa is TRUE?

a) A BMI less than 18 kg/m2 is required for the diagnosis
b) People with AN and diabetes may increase their insulin dose to suppress their appetite
c) Depressed patients who develop severe weight loss (BMI

A

d) Amenorrhoea is a significant symptom in females with anorexia

Feedback:

Disturbance of the hypothalamic-pituitary-gonadal axis leads to amenorrhoea or arrest of puberty. Libido is low. In men, there may be a loss of morning erections.

54
Q

People with anorexia nervosa are by definition malnourished.
Clinical signs suggesting malnutrition in AN include all of the following EXCEPT::

a) Postural hypotension
b) Peripheral oedema
c) Lanugo hair
d) Hypercholesterolaemia
e) Tachycardia

A

e) Tachycardia

Feedback:

People with anorexia nervosa typically become bradycardic, not tachycardic.

55
Q

Mr Henry Rimmel is a 45 year old man whose 15 year old daughter Neela has recently been diagnosed with anorexia nervosa. Mr Rimmel calls the GP surgery where you are on placement as a final year medical student to discuss her treatment and what is going to happen next. The GP asks you to take the call.
Regarding the treatment of AN, which of the following statements is TRUE?

a) Inpatient treatment is indicated if BMI is

A

d) Motivational interviewing is useful in patients who lack insight into their disorder

Feedback:

Motivational interviewing (MI) is a form of counselling that aims to empower the person to change. It works by helping them to recognize the gap between where they are now and where they want to be, and is based on a supportive but challenging therapeutic relationship.
The decision to provide inpatient treatment is made on a patient-by-patient basis. It may be necessary if the patient's BMI is
56
Q

Laura is a 35 year old woman who gave birth to her second child 2 months ago. She attends your GP surgery and tells you that she has lost interest in sex, despite previously enjoying an active sex life.
Which of the options below is LEAST likely to have caused her problem?

a) Childbirth
b) Childhood sexual abuse
c) Depression
d) Physical illness
e) Medication

A

b) Childhood sexual abuse

Feedback:

A problem from childhood such as abuse is more likely to cause a primary low libido - i.e. “normal” function is never gained. Laura has secondary low libido, i.e. her problems follow a period of normal function - when she regarded her libido as “normal”.

57
Q

Having diagnosed Laura with secondary low libido due to relationship problems following childbirth you look into treatment options.
Which of the options below is the MOST helpful treatment for low libido?

a) Antiandrogen therapy
b) Serotonergic antidepressants
c) Self-exploration therapy
d) Cognitive behavioural therapy (CBT)
e) Sensate focus therapy

A

e) Sensate focus therapy

Feedback:

In sensate focus therapy, intercourse is initially banned, and a couple are taught to focus initially just on non-genital touch for pleasure and relaxation. The emphasis is on enjoyment, intimacy, and exploration of each person’s needs, rather than on the act of intercourse itself. Genital touching occurs later on, and eventually leads to sexual intercourse.

58
Q

Dennis is a 22 year old mini-cab driver who presents with a year’s history of erectile dysfunction.
Which of the following options is LEAST likely to have caused the symptoms?

a) Substance misuse
b) Depression
c) Hypertension
d) Performance anxiety
e) Alcohol

A

c) Hypertension

Feedback:

Though not impossible, it would be unusual for a man of 22 to be impotent due to hypertension, which is more likely to be associated with older patients’ problems.

59
Q

You are a junior doctor working in a GP practice. Peter Wilkes comes to talk to you. His girlfriend Emma gave birth 3 days ago and although she seemed “completely normal” before the birth, he is concerned as she seems very emotional and prone to mood swings. His mother suspects that Emma may be depressed.
Choose the percentage of new mothers affected by this disorder.

a) Up to 10%
b) Up to 25%
c) 25 - 50%
d) 50 - 75%
e) 75 - 100%

A

d) 50 - 75%

Feedback:

This is postnatal “blues”. It is too early for postnatal depression.

60
Q

Asuncion Jelinek is a 40 year old single mother who attends your GP surgery, 2 months after giving birth to her son Fernando. She recently separated from her husband and tells you that she has no friends in England, having only moved here recently. Like her mother, Asuncion suffered depression in her thirties.
The risk of postnatal depression is increased by all of the following, EXCEPT:

a) Personal history of depression
b) Older maternal age
c) Family history of depression
d) Concurrent life events
e) Poor social support

A

b) Older maternal age

Feedback:

Younger maternal age is a predisposing factor.

61
Q

Dominique Smith is a 27 year old woman who gave birth to her son, Bronx-Baloo, a week ago. She now appears to be hearing voices and is terrified of the staff. Her speech is rambling and difficult to follow and she is very restless. The consultant is concerned that she has developed puerperal psychosis.
Regarding puerperal psychosis, which of the following statements is FALSE?

a) Once present, symptoms tend to be constant
b) Substance misuse is a differential diagnosis
c) Pharmacotherapy is indicated
d) Symptoms rarely last more than 3 months
e) Electroconvulsive therapy may be indicated

A

a) Once present, symptoms tend to be constant

Feedback:

Symptoms fluctuate rapidly and dramatically

62
Q

You are working in a GP surgery. A 27 year old woman, Sandra Eckhart, attends an appointment made by her husband Josh. With them is their first child, born via emergency caesarean section after a failed ventouse delivery 8 weeks ago. She was a healthy, full-term baby who did not require any specialist input after birth. Josh is concerned about Sandra’s mood and sleep disturbance. During the interview she seems tearful and avoids eye contact. She asks to be referred to a paediatrician to ‘have the baby checked out.’
Which of the following statements is TRUE?

a) Post partum ‘blues’ are the most likely diagnosis
b) Suicide is a rare cause of death in new mothers
c) Breastfeeding is an absolute contraindication to pharmacotherapy
d) An urgent referral to paediatrics should be made to reassure Sandra
e) It is essential to assess Sandra’s interaction with her child

A

e) It is essential to assess Sandra’s interaction with her child

Feedback:

This is a vital part of the risk assessment.

63
Q

Kelly is a 30 year old woman with bipolar affective disorder. She is currently well and concordant with lithium. She presents to you in general practice as she and her husband are planning to start a family.
Which of the following is TRUE?

a) Pregnancy will increase Kelly’s risk of relapse by up to 8-fold
b) Kelly should discontinue her medication to avoid risk of harm to the foetus
c) Bipolar affective disorder does not increase the risk of puerperal psychosis
d) Lithium is generally safe in pregnancy and breastfeeding
e) There is a 30% chance of her child suffering bipolar affective disorder

A

a) Pregnancy will increase Kelly’s risk of relapse by up to 8-fold

Feedback:

A full discussion, with Kelly’s psychiatrist and an obstetrician, is needed to make a proper risk assessment and support her in deciding whether or not she wishes to continue with lithium while attempting pregnancy. There are risks to her foetus of Ebstein’s anomaly from taking lithium (especially in the first trimester), though the risk is fairly low and abnormalities are now operable. Stopping her lithium (especially suddenly) may precipitate a manic relapse, and this could be more risky than any harm to the baby from the lithium. The decision is ultimately Kelly’s - and she will need extra support and reviews from obstetrics and psychiatry, whatever she decides to do.
Page reference: 32, 45, 196, 197

64
Q

Martin is a very active ten year old boy, who has had difficulties making friends at school. His parents are worried that he stutters and suspect he is being bullied at school because of his appearance. His teachers report that Martin is struggling with lessons and are concerned that he might have a learning disability.
Their GP has suggested genetic counselling as she suspects that Martin may have a genetic disorder.
Which of the following options is LEAST likely to cause or mimic a learning disability?

a) Fragile X syndrome
b) Autism
c) Gilles de la Tourette syndrome
d) Epilepsy
e) Schizophrenia

A

c) Gilles de la Tourette syndrome

65
Q

Martin’s parents have given their consent for further investigation of the cause of Martin’s suspected learning disability.
Which of the following options is MOST likely to be helpful when investigating learning disabilities?

a) Full neurological assessment.
b) MRI / CT head.
c) FBC, U&E, LFT, TFT, bone profile.
d) Developmental history and functional assessment of skills.
e) Genetic testing.

A

d) Developmental history and functional assessment of skills.

Feedback:

Parent statements and school reports are invaluable parts of the assessment.

66
Q

The geneticists diagnose Martin with Fragile X syndrome.
In terms of prognosis, which of the following options MOST accurately reflects Martin’s future?

a) Individuals with Fragile X lack the ability to learn or imitate and will progressively become more forgetful.
b) Most behavioural problems increase throughout the lifespan.
c) The life expectancy is similar to that of the general population.
d) The extent of support determines the degree of limitation.
e) The outlook for patients with fragile X syndrome is independent of when the condition is diagnosed.

A

d) The extent of support determines the degree of limitation.

Feedback:

This is true of learning disabilities in general.

67
Q

21 year old Jonathan Spidee comes to the GP surgery, accompanied by his mother. Jonathan has been distressed while using the toilet and bathing over the last two weeks. He has a known diagnosis of Down syndrome.
Which of the options below is the MOST appropriate way for you to communicate with Jonathan?

a) Address questions to Jonathan’s mother, allowing Jonathan to add his point of view where helpful.
b) Address him as “Johnny” to ensure you do not intimidate him.
c) Address questions to Jonathan allowing his mother to remain as a passive observer throughout the consultation.
d) Assess Jonathan with a chaperone, asking his mother to leave for part of the assessment.
e) Assess Jonathan, with a chaperone, asking his mother to remain present throughout the assessment.

A

d) Assess Jonathan with a chaperone, asking his mother to leave for part of the assessment.

Feedback:

Jonathan’s symptoms should ensure the opportunity for privacy during the consultation - for example, his distress may relate to urethral discharge or other symptoms of a sexually transmitted infection, making him unwilling to share this in front of his mother. Caring parents may be very used to providing intimate care to their sons or daughters with learning disabilities, but this does not mean that your patients lose the right to privacy or confidentiality. You probably wouldn’t want your parents to be present during a genital examination!

68
Q

Jenny is diagnosed with a mild learning disability.
Which of the following statements is FALSE?

a) Mild disability is under-diagnosed.
b) Jenny will probably need to live with her family for the rest of her life.
c) Jenny’s IQ level is between 50-69.
d) Jenny is at increased risk of schizophrenia, compared with the general population
e) Developmental delay is associated with mild learning disability.

A

b) Jenny will probably need to live with her family for the rest of her life.

Feedback:

With appropriate support, many people live and work independently.

69
Q

A young mother is worried about her 3 year old son, Yusuf, who prefers to play alone without interacting with other children. He speaks very little but is overactive and easily distracted. He is distressed by changes in his daily routine.
Which of the following options is LEAST likely to guide you to your diagnosis?

a) Obstetric history
b) EEG
c) Neuropsychological assessment
d) Speech and language assessment
e) Hearing tests

A

b) EEG

70
Q

Casper is 6 years old and has been diagnosed with Asperger’s syndrome. His parents have been doing some reading on the internet and are quite worried about Caspar’s future.
Which of the statements below is INCORRECT with regards to a diagnosis of Asperger’s syndrome?

a) It is an autistic spectrum disorder.
b) Social skills are normal but language is poor.
c) Male to female ratio is 8:1.
d) Interests are commonly restricted
e) Individuals with this syndrome have normal IQ.

A

b) Social skills are normal but language is poor.

Feedback:

In Asperger’s syndrome, language and IQ are normal but people have poor social skills and restricted interests.

71
Q

4 year old Molly has been brought in to see the GP by her parents as they are worried about her development. She appears extremely shy and tearfully clings to her father’s legs, trying to hide behind him.
Which of the options below is the MOST helpful way of approaching Molly and her family?

a) Focus your attention on Molly’s father.
b) Chase her around the room in a playful manner.
c) Ask Molly to draw you a picture.
d) Try to get her interested in a conversation by asking open questions.
e) Explain that doctors aren’t strangers, so Molly can trust you.

A

a) Focus your attention on Molly’s father.

Feedback:

This will help Molly to relax and adjust to your presence, without feeling under scrutiny herself. Giving her the opportunity to draw a picture is a close second choice, though extremely shy children may resist even this interaction.

72
Q

14-year old David has been acting ‘rebelliously and then some’ for the last six years according to his teacher. His mother died when he was very young and his father has been in and out of prison most his life. David lives with his grandmother who has a hard time coping with him.
Regarding conduct disorder (CD) which of the options below is UNTRUE?

a) It is four times more common in boys.
b) The behaviour is persistently antisocial.
c) It runs in families.
d) A CD gene has been identified on chromosome 6.
e) The behaviour is often learned.

A

d) A CD gene has been identified on chromosome 6.

Feedback:

Although CD runs in families a single gene has not yet been identified. There is most likely a mixture of learned behaviour from observing parents and siblings, as well as shared environmental and genetic factors.

73
Q

4 year old Jack has been diagnosed with autism and his mother is very keen to know about the prognosis.
Which of the options below is TRUE of the prognosis in autism?

a) Anticonvulsants slow the progression rate of autism.
b) An IQ of 90 is a poor prognostic indicator.
c) 1-2% of people gain full independence later in life.
d) The Measles-Mumps-Rubella (MMR) vaccine may improve the prognosis.
e) Positive reinforcement is of minimal benefit in autism, due to comorbid cognitive problems.

A

c) 1-2% of people gain full independence later in life.

74
Q

Which of the following is not characteristic of personality disorders?

a) Pervasive
b) Persistent
c) Distressing
d) Onset in adulthood
e) Problems in maintaining employment

A

d) Onset in adulthood

Feedback:

There should be evidence of personality disorder from childhood or adolescence. A sudden personality change suggests that something else is going on (e.g. organic cause / functional mental illness). If someone has always coped well until a certain stressful period, you should not diagnose personality disorder - most of us can look a little “personality disordered” when dealing with acute stressors!

75
Q

Which of the following personality disorders is more common in women than men?

a) Paranoid personality disorder
b) Schizoid personality disorder
c) Antisocial personality disorder
d) Anankastic personality disorder
e) Emotionally unstable personality disorder - borderline type

A

e) Emotionally unstable personality disorder - borderline type

Feedback:

Men have higher overall rates of personality disorder, particularly cluster A (paranoid, schizoid), dissocial or anankastic types. Histrionic or emotionally unstable borderline personality disorders are more common in women.

76
Q

Defence mechanisms are unconscious strategies that are used to manage uncomfortable feelings.
Psychological defence mechanisms include all of the following except:

a) Acting out
b) Splitting
c) Targeting
d) Fantasizing
e) Reaction formation

A

c) Targeting

77
Q

Which of the following is not a recognized treatment for personality disorders?

a) Cognitive Analytical Therapy
b) Cognitive Behavioural Therapy
c) Rationalization Therapy
d) Therapeutic communities
e) Psychoanalytical psychotherapy

A

c) Rationalization Therapy

Feedback:

This doesn’t exist. The others are all recognized treatments.