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Resp Path > J kinder general Abx > Flashcards

J kinder general Abx Flashcards

1
Q

Inhibitors of cell wall synthesis (5 classes)

A 
Penicillins
Cephalosporins
Carbapenems
Monobactams
Glycopeptides
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2
Q

B Lactams

A

MOA: Bind PBP and prevent last step of D-Ala-D-Ala in cell wall synthesis

Resistance:
Structural PBP change
G neg 9inability for it to reach cell wall)
Drug efflux pumps

Destroyed by B lactamases

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3
Q

Pencillins
MOA
AE (6)

A 
MOA: PBP and cell wal inhibition
AE: Allergic Rxn/Anaphylaxis
Interstitial nephritis
N/V/D
C. diff
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4
Q

Cephalosporins
MOA
Coverage in the 4
AE (3)

A

MOA: PBP and cell wall synthesis inhibitor

1->4 increasing coverage of gram negatives

AE: risk of X-rxn w/ penicillins
Diarrhea
Intolerance to alcohol

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5
Q

Carbapenems

MOA
AE(4)

A

MOA: PBP and cell wall synthesis

AE: N/V
Seizures
Hypersensitivity

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