J. Cell Mediated Immunity Flashcards
0
Q
Where does the cytotoxic T cell attach its co-receptor and T cell receptor to the APC
A
Co-receptor—> MHC I
T cell receptor—> displayed epitope (antigen)
1
Q
Structure of cytotoxic T cell
A
CD8 co-receptor
T cell receptor
2
Q
After connecting with a APC the cytotoxic T cell is?
A
Activated and goes on patrol
3
Q
When the cytotoxic T cell finds a cell, what does it do?
A
Touches its epitope
If host cell is infected, forces cell to perform apoptosis
4
Q
Apoptosis
A
Self destruction
5
Q
Perforins
A
Proteins that punch holes into the infected cells membrane
6
Q
Granzymes
A
Chemicals that cause infected cell to self destruct (suicide), programmed cell death
