IV Therapy (Class 11) Flashcards
Total body fluid
- Varies according to age, lean body mass and sex.
- Contained in 2 main compartments: Intracellular (IC) and Extracellular (EC)
- Total body fluid is 65% of body weight
- IC fluid is 40% of body weight
- EC fluid 20% of body weight and can be broken down into (1) interstitial fluid (around cells) that is 15% and (2) plasma (Intravascular) that is 5%.
Why do you administer IV fluids?
- To replace fluid and electrolytes (dehydration)
- Administer medications (IV push and IVPB’s - antibiotics, other medications)
- Administer blood and blood products
- Adequate nutrition (TPN)
Water in the body functions primarily as a(an) what?
- Medium to transport nutrients to cells and wastes from cells.
- Transport for hormones, enzymes, platelets, RBC’s, WBC’s
- Facilitator for cellular metabolism
- Solvent for electrolytes and nonelectrolyte solutes
- Aid to maintain normal body temperature
- Facilitator for digestion and promote elimination.
Solvent, Solute, and Solution
Solvent (a liquid, solid, or gas) dissolves the Solute (another solid or gas) —> results in a Solution
Intravenous Therapy
- IV solutions consist of water (the solvent) containing one or more types of dissolved particles (or solutes)
- Solvents most commonly dissolved in IV solutions are sodium chloride and dextrose.
- Solutes that dissolve in water and disassociate into charged particles (Na+, Cl-, K+) are electrolytes.
-IV solutions also contain particles and have an osmolarity which is measure against normal blood serum.
Electrolytes
- Substances capable of breaking into electrically charged ions when dissolved in solution (K+, Na+, Cl-, Ca+)
- Milliequivalent (mEq) is one unit of measure for electrolytes
- Necessary for metabolism, cell functioning, acid base balance, and water distribution.
Osmosis
- Is the movement of water across the intravascular capillary membranes to the interstitial spaces and across the cell membranes and back to the intravascular capillary space.
- Through osmosis, water moves from area of high concentration of water (low electrolyte concentration) to an area of low concentration (high electrolyte concentration).
- Osmosis is the movement of water through a semipermeable membrane to a higher concentration of solutes.
- Water easily moves through cell membranes by osmosis
Osmolality
The measure of solute (dissolved particles such as sodium, chloride, potassium, and glucose) concentration in the solvent (blood).
-It is calc as the osmosis of these solutes per kilogram of solvent (the solution they are dissolved in)
Tonicity
-The measure of the osmotic pressure gradient between 2 solutions. Tonicity implies 2 fluids separated by a membrane and is the ability of a solution to exert osmotic pressure across a membrane.
- Concentration of ions in a solution
- Tonicity range for IV fluids is 103->560 mOsm/L
Isotonic Solution
- If IV solution has approximately same osmolarity as blood then it is isotonic.
- Tonicity: 280-300 mOsm
- Causes fluid to remain in the intravascular (IV) compartment.
- Used to increase intravascular volume during acute blood loss, GI bleeding, to support BP when patient is hypotensive, hypovolemic
- NS or 0.9% sodium chloride (310 mOsm)
- Lactated Ringers (LR) solution (275 mOsm)
- D5W (250 mOsm) –> D5W isotonic in IV bag but quickly becomes hypotonic in body because body uses the glucose, which leaves free water.
Hypotonic Solution
- IV solutions with fewer dissolved particles than blood is hypotonic.
- Tonicity:Less than 280 mOsm
- Causes fluid to move out of the intravascular space and into cells: cells swell and burst
- Used for cellular dehydration. Fluid goes into cells.
- None of the hypotonic solutions have dextrose (D): 0.25% NS, 0.33% NS (112 mOsm), 0.45% NS (154 mOsm)
Hypertonic Solution
- IV solutions with more dissolved particles than blood is hypertonic.
- Tonicity:Above 300 mOsm
- Causes fluid to move out of cells into IV space: cells shrivel and shrink
- Used to shift fluid from intercellular and interstitial spaces into intravascular space in order to reduce cellular edema, and vascular volume overload.
- Solutions all have dextrose (D, sugar) sugar makes you hyper —> D5/0.45NS (405 mOsm), D10W, D5/NS (560 mOsm), D5/LR, D5/0.2NS, D5/0.33NS
What are the classifications of IV solutions?
(1) Crystalloids: dextrose, saline, LR
(2) Colloids: volume expanders - dextran, plasmanate, Hespan, Voluven, blood.
(3) Blood and blood products: whole, packed, plasma, albumin
(4) Lipids: balance nutritional needs - total parenteral nutrition or TPN
Explain the basic concept of total parenteral nutrition.
- This is a last resort feed them this way only if you have tried everything else first.
- High glucose (sugar) content cause complications, prone to infections.
- Get nutrition totally through veins.
- When pt cannot be fed by the other preferred routes, TPN bypass the process of eating and digestion.
- Receives nutritional formulas containing salts, 25%-70% dextrose, amino acids, lipids, added vitamins, minerals, and electrolytes.
Peripheral IV Site
- Over-the-Needle catheter for brief use with 1-2 ports.
- Change dressing every 72 hours
- New site Q72H (or 96 hours when stabilization device used) sooner if complications.
- Hand or arm sites