IV Medications

Question 1

Define Vesicant

Answer 1

A drug that will cause severe tissue damage if the catheter falls out of the veins, allowing the dug to seep into the surrounding tissue

Question 2

List Vesicants (3)

Answer 2

Vasopressors (DA, NE)

Anthracyclines (doxorubicin)

Vinca alkaloids (vincristine, vinblastine)

Question 3

What is DEHP

Answer 3

Makes the plastic bag more flexible, but can leach from the container and into the solution.

DEHP is toxic and can harm the liver and testes

Question 4

Key drugs with leaching/adsorption/absorption issues with PVC containers

Answer 4

Leaches Absorb To Take In Nutrients

Lorazepam
Amiodarone
Tacrolimus
Taxanes
Insulin
Nitroglycerin

Question 5

Drugs to use in saline

i.e. Cannot use dextrose with these drugs

Answer 5

A DIAbetic Can’t Eat Pie

Ampicillin
Daptomycin
Infliximab
Ampicilin/Sulbactam
Caspofungin
Ertapenem
Phenytoin

Question 6

Drugs to use in dextrose

i.e. Cannot use saline with these drugs

Answer 6

Obese Baker Avoids Salt

Oxaliplatin
Bactrim
Amphotericin
Synercid

Question 7

Drug combos that form Precipitates

Answer 7

Calcium (LR) + Ceftriaxone

Calcium + Phosphate

Question 8

What do precipitates cause in patients

Answer 8

Emboli