IV key points Flashcards
ideal agent
anxiolysis non-irritant no SEs sedation quick onset ease of administration quick recovery low cost
BZD action
acts on receptors in CNS to enhance effect of GABA (inhibitory CNS neurotransmitter)
- prolongs time for receptor repolarisation
effects of BZDs
respiratory - resp depression
CNS - CNS depression and muscle relaxation
CV - reduce bp by muscle relaxation, increase hr due to baroreceptor reflex compensating for bp fall
SEs of BZDs
drug interactions
tolerance and dependence
- shouldn’t see in single session
sexual fantasies (rare)
disadvantages of diazepam as a sedation agent
pain on injection
long recovery
risk of rebound sedation
unpredicatble
midazolam prep
5mg/5ml (1mg/ml)
advantages of midazolam
painless on injection more rapid onset more potent than diazepam - less working time but safer extra-hepatic metabolism in bowel so less affected by liver disease than some quicker recovery reliable
sedation team
operator - sedationist
2nd trained person e.g. nurse
= neither can leave room
3rd person - runner and reception
roles of nurse
calm support chaperone pre and post op instruction machine safety checks monitoring recovery emergencies
role of cannula
deliver sedative agent
why is an indwelling cannula mandatory?
may be needed for emergency
more secure, rarely blocks
why shouldn’t a butterfly cannula be used?
used for taking blood - one quick use
easy but clots and obstructs
easily dislodged
flashback
bit of blood comes back into reservoir of cannula
shouldn’t be much resistance
advantages of dorsum of hand
accessible
superficial and visible
no nearby arteries/nerves/joints
disadvantages of dorsum of hand
poorly tethered - move about a bit
affected by peripheral vasoconstriction so may need to warm hand
small veins
more painful