IV key points Flashcards

1
Q

ideal agent

A
anxiolysis
non-irritant
no SEs
sedation
quick onset
ease of administration
quick recovery
low cost
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2
Q

BZD action

A

acts on receptors in CNS to enhance effect of GABA (inhibitory CNS neurotransmitter)
- prolongs time for receptor repolarisation

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3
Q

effects of BZDs

A

respiratory - resp depression
CNS - CNS depression and muscle relaxation
CV - reduce bp by muscle relaxation, increase hr due to baroreceptor reflex compensating for bp fall

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4
Q

SEs of BZDs

A

drug interactions
tolerance and dependence
- shouldn’t see in single session
sexual fantasies (rare)

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5
Q

disadvantages of diazepam as a sedation agent

A

pain on injection
long recovery
risk of rebound sedation
unpredicatble

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6
Q

midazolam prep

A

5mg/5ml (1mg/ml)

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7
Q

advantages of midazolam

A
painless on injection
more rapid onset
more potent than diazepam
 - less working time but safer
extra-hepatic metabolism in bowel so less affected by liver disease than some
quicker recovery
reliable
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8
Q

sedation team

A

operator - sedationist
2nd trained person e.g. nurse
= neither can leave room
3rd person - runner and reception

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9
Q

roles of nurse

A
calm support
chaperone
pre and post op instruction
machine safety checks
monitoring
recovery
emergencies
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10
Q

role of cannula

A

deliver sedative agent

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11
Q

why is an indwelling cannula mandatory?

A

may be needed for emergency

more secure, rarely blocks

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12
Q

why shouldn’t a butterfly cannula be used?

A

used for taking blood - one quick use
easy but clots and obstructs
easily dislodged

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13
Q

flashback

A

bit of blood comes back into reservoir of cannula

shouldn’t be much resistance

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14
Q

advantages of dorsum of hand

A

accessible
superficial and visible
no nearby arteries/nerves/joints

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15
Q

disadvantages of dorsum of hand

A

poorly tethered - move about a bit
affected by peripheral vasoconstriction so may need to warm hand
small veins
more painful

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16
Q

antecubital fossa - where should you keep?

A

lateral to biceps tendon

17
Q

advantages of antecubital fossa

A

larger veins, better tethered to CT
more predictably sited
less painful
less venoconstriction

18
Q

disadvantages of antecubital fossa

A

access, joint immobilisation
potential nerve damage/intra-arterial injection
less stable

19
Q

pre-sedation process

A
Ametop gel
pre-op pulse and bp
confirm
 - escort
 - travel home
 - responsibilities
 - reconfirm consent
get high vol aspiration set up
emergency drugs ready
 - flumazenil
 - means of ventilation
20
Q

what should be done with the cannula before sedation?

A

flush with saline

21
Q

midazolam dose

A

2mg bolus

1mg increments every 60s until suitable level of sedation

22
Q

suitable sedation signs

A
slurring and slowing of speech
relaxed
delayed response to commands
willingness to accept tx
Verrill's sign
Eve's sign
23
Q

Verrill’s sign

A

ptosis - drooping eyelids

24
Q

Eve’s sign

A

loss of motor coordination

- get pt to close eyes, arms out wide then touch nose with both fingers, often miss nose

25
Q

therapeutic dose of midazolam varies with:

A

sleep
alcohol
stress
drugs

26
Q

max midazolam dose

A

7.5mg generally, usually a lot less

27
Q

how long useful sedation for tx do you get with midazolam?

A

30-45mins

28
Q

flumazenil prep

A

500mcg/5ml

29
Q

flumazenil dose

A

200mcg then 100mcg increments every 60s until a response is seen
don’t give too quickly as pt may become v agitated

30
Q

flumazenil cautions

A

shorter 1/2 life than midazolam so risk of resedation
- keep pt for longer - 1-4hrs
caution in suspected BZD allergy

31
Q

recovery

A
escort 2nd person
60mins after last increment
continue monitoring (keep cannula)
 - write down times you give everything
remove cannula (warn bruising)
ensure can walk unaided
give escort POIs
32
Q

respiratory depression management

A
Stop tx
deep breaths (low 90s) - talk, shake, hurt
O2 - 2l/min via nasal cannulae
 - can continue tx with this in if O2 sats improve
O2 - 5l/min via Hudson mask
flumazenil (<90%)
ambu bag
airways