Item 116 : pathologies auto-immunes Flashcards

1
Q

Ac Maladie de Basedow

A

Ac anti récepteur de la TSH

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2
Q

Ac Thyroïdite de Hashimoto

A

Ac anti-TPO

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3
Q

Ac Diabète de type 1

A

Ac anti-insuline / anti-ilots / anti-GAD

La présence d’au moins 1 type d’Ac fait le diagnostic de l’étiologie auto-immune du diabète

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4
Q

Ac Insuffisance surrénale lente

A

Ac anti-21-hydroxylase

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5
Q

Ac Maladie coeliaque

A

Ac anti-gliadine / anti-endomysium, etc

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6
Q

Ac MICI

A

ASCA (M. de Crohn) / ANCA (RCH)

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7
Q

Ac hépatite auto-immune

A

Ac anti-LKM1 (type 2)

Ac anti-LC1

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8
Q

Ac cirrhose biliaire primitive

A

Ac anti-mitochondries (M2)

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9
Q

Ac Maladie de Biermer

A

Ac anti-estomac :
Ac anti cellule pariétale (très sensible peu spécifique)
Ac anti facteur intrinsèque (très spécifique peu sensible)

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10
Q

Ac pemphigus

A

Ac anti desmogléine 3

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11
Q

Ac Vitiligo

A

Ac anti-mélanocyte

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12
Q

Ac Myasthénie

A

Ac anti-récepteur de l’ACh

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13
Q

Ac Sd de Goodpasture

A

Ac anti-membrane basale glomérulaire

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14
Q

Ac Sd de Guilain Barré

A

Ac anti-ganglioside M1 et GD1b

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15
Q

Ac myxoedème primaire = thyroïdite atrophique

A

Ac anti TPO

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16
Q

Ac granulomatose de Wegener

A

c-ANCA (p-ANCA rare++)

17
Q

Ac PAM

A

c-ANCA + p-ANCA

+/- Ac anti myélopéroxdase anti-protéinase 3

18
Q

Ac Churg & Strauss

A

c-ANCA + p-ANCA

+/- Ac anti myélopéroxdase anti-protéinase 3

19
Q

Ac Polyarthrite Rhumatoïde

A

Facteur rhumathoïde

Ac anti-CCP (peptide cyclique citrulliné)