Isovolemic HemoDilution Flashcards
What is the primary cardiovascular response to maintain oxygenation during isovolaemic hemodilution?
Increased cardiac output (CO): The heart increases both heart rate and stroke volume to pump more blood per minute, ensuring that oxygen delivery is maintained despite a reduction in RBC concentration
How do tissues extract more oxygen during isovolaemic hemodilution?
Enhanced oxygen extraction: Tissues increase the percentage of oxygen they extract from the blood, utilizing a greater amount of the oxygen that is carried by hemoglobin.
What happens to the oxyhemoglobin dissociation curve during isovolaemic hemodilution?
The oxyhemoglobin dissociation curve shifts to the right (Bohr effect), making it easier for hemoglobin to release oxygen to tissues, especially in the presence of higher CO₂, H⁺ ions, and lactic acid.
How does hemodilution affect blood viscosity and oxygen delivery?
Reduced blood viscosity: Hemodilution decreases the thickness of the blood, allowing it to flow more easily through small capillaries, improving microcirculation and oxygen delivery to tissues.
How does the body prioritize oxygen delivery during hemodilution?
Redistribution of blood flow: The body redirects blood flow to vital organs like the heart, brain, and kidneys, ensuring these organs receive sufficient oxygen even when overall oxygen-carrying capacity is reduced.
What changes occur in tissue oxygen utilization during hemodilution?
Increased tissue oxygen utilization: Tissues adapt by maximizing the efficiency of oxygen use, especially in organs with high oxygen demands, like the brain and heart.
