ISBT TERMINOLOGY OF RED BLOOD CELL SURFACE ANTIGENS Flashcards
T OR F.
ISBT= 6 numbers
First 3: Blood group system
Last 3 specific antigen
True
Most common cause of HTR and HDN
ABO blood group
may also appear as a “halo”
or “puff of smoke” of unagglutinated RBCs as the RBC button is dislodged from the test tube bottom
Mixed field
Causes of mixed field
non-ABO-type specific RBCs, ABO subgroups (A3), and bone marrow or hematopoietic stem cell transplantation
precursor structure on which A and B antigens are made
H antigen
Not part of the ABO system but their inheritance influence A and B antigen expression
H and Se genes
Amount of H (greatest to least)
O, A2, B, A2B, A1, A1B
Frequencies
O,A,B,AB
Controlling genes of Type 1 chain
H,A,B,Se, Lewis
Source of anti-B lectin
Bandeiraea simplicifolia
Anti-A1 lectin source
Dolichos biflorus
Has a higher titer compared to Anti-A or Anti-B alone
Anti AB