IS Flashcards
Innate Immunity 1st line of defense
External: Physical: ‘‘CIMC’’ and Biochemical: ‘‘LESLy’’
Innate Immunity 2nd line of defense ;cellular
'’B E Ph A Nk’’
Innate Immunity 2nd line of defense ; Humoral
'’Com Cy Ly Pro Be’’
Adaptive 3rd line: cellular
'’Ly TBA P’’
Adaptive 3rd line: humoral
'’Cy An Co’’
chemical messenger that causes cells to migrate in a particular direction
Chemotaxis
Adherence of cells to vessel wall
Margination
movement of cells from blood to tissues
Diapedesis
directed margination of a cell in response to a chemical stimulus
Chemotaxis
cells capture and ingest foreign particles to eliminate invading pathogens
Phagocytosis
critical cytokine for orchestrating the immune response, particularly in promoting antibody production, allergic reactions, and alternative macrophage activation.
IL-4
most effective APC and the most potent phagocytic cell
Dendritic cells
intraglomerular mesangial cells
Kidneys
unique receptors to attach to microorganisms
TLRs
Normal chemokinesis (movement); Abnormal chemotactic(migration)
Job Syndrome
test for chemotactic (migration) activity of phagocytes
Boyden Chamber assay
site where most blood cells mature including B and NK cells
Bone marrow
for B cell activation and differentiation
IL-7
synthesis of heavy chain occurs in what stage of B cell maturation
Pre-B cell
Surface marker of Pro-B cell
CD 19, 45R, 43, 24 AND C-kit
coding for light chains on either Chromosome 2(kappa) and 22(lambda) has taken place by this stage
Immature B-cell
important for intraction of B cell with T cells
CD 40
MHC class II
