Iron Flashcards

1
Q

chemistry of iron

A

Fe2+- ferrous - reduced -soluble

Fe3+- ferric - oxidized -insoluble

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2
Q

distribution of iron in the body

A
  • 65% hemoglobin (blood)
  • 10% myobglobin (muscle)
  • 1-5% enzymes
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3
Q

types of iron

A
heme:
--increase bioavalability
--hemoglobin/hemoglobin 
--animal sources 
non-heme:
--decrease bioavailability 
--plant sources
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4
Q

factors that affect iron absorption

A
  • dietary iron content
  • bioavailability
  • storage iron
  • disease or pregnancy
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5
Q

enhancing factors of iron absorption

A
  • animal protein
  • V-C
  • fructose/sorbitol
  • cysteine
  • low iron stores
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6
Q

inhibiting factors of iron absorption

A
  • Ca
  • oxalate/phytate/fiber
  • lack of protein
  • coffee/tea
  • high iron storage
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7
Q

iron transport

A

-bind to transferrin (blood protein) in blood

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8
Q

iron storage

A
  • liver/spleen/bone marrow

- ferritin

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9
Q

functions of iron

A
  • oxygen transport
  • cofactor
  • normal brain
  • immune function
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10
Q

enzymes that require iron

A
  • cytochromes
  • monooxygenases
  • dioxygenases
  • peroxidases
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11
Q

iron deficiency w/o anemia

A
  • depletion of bone marrow
  • decrease ferritin
  • normal hemoglobin

symptoms:

  • impaired cognitive tasks
  • behavioral disturbances
  • short attention span
  • impaired immune system
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12
Q

iron deficiency w/ anemia

A
-histology-microcytic/hypochromia
symptoms:
-fatigue 
-palpitation
-rapid breathing
-decrease athletic performance 
-inflammation in corner of mouth  
-pica
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13
Q

population at risk for iron deficiency

A
  • infants/young children being breastfed
  • adolescents:
  • -growth spurt
  • -periods
  • -in utero
  • women at child bearing age
  • pregnant women in their trimester
  • chronic blood loss
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14
Q

iron recommendation

A

RDA- men= 8 mg/d
-women= 18 mg/d
UL= 45 mg/d

typical western diet= 5-7 mg/1000 kcals

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15
Q

iron food sources

A
  • clams
  • beef
  • oysters
  • shellfish
  • lentils
  • beans
  • poultry
  • fish
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16
Q

iron toxicity

A
  • hemochromotosis:
  • -stage 1: blood in vomit, belly pain, diarrhea
  • -stage 2: improvement
  • -stage 3: body in shock
  • -stage 4: death
  • treatment- blood transfusion
  • caused by- Fe overload (failure to overload)
  • short term- fatigue, decreased appetite, decreased memory
  • long term- organ failure
17
Q

assessment of nutriture for iron

A
  • plasma ferritin= <12 mg- early stages
  • total iron bind mg capacity (TIBC)= >400 micrograms/dL
  • serum iron= <50 micrograms/dL
  • hemoglobin= <12-13 g/dL- late stages