IRON 2 Flashcards
What is the role of iron in CNS development?
Iron is essential for CNS development
How is iron stored in the body?
Iron is stored in the body mainly in the form of ferritin and hemosiderin.
What is ferritin?
Ferritin is a globular protein that serves as the main storage form of iron
What is the recommended daily dietary allowance of iron?
The recommended daily dietary allowance of iron is 1-2 mg/day.
What happens to iron absorption when iron stores are high?
When iron stores are high
What are the common inhibitors of iron absorption?
Common inhibitors of iron absorption include phytates and oxalates in cereals and legumes
What is the function of transferrin?
Transferrin is a glycoprotein that facilitates the transportation of iron in plasma by binding to iron and delivering it to various cells.
What triggers increased production of hepcidin?
Increased production of hepcidin is triggered by inflammation via interleukin 6.
What is the consequence of impaired iron absorption?
Impaired iron absorption can lead to iron deficiency
What is hereditary hemochromatosis?
Hereditary hemochromatosis is a genetic condition that causes excessive absorption of iron from the diet
What is the fate of iron once absorbed into enterocytes?
Once absorbed into enterocytes
How is iron recycled in the body?
Iron is recycled in the body through the phagocytic action of macrophages
What are the average daily iron losses in males and females?
The average daily iron loss is 1 mg/day for males and 1-1.5 mg/day for females.
What is the role of vitamin C in iron absorption?
Vitamin C enhances the absorption of non-heme iron by reducing ferric iron (Fe3+) to ferrous iron (Fe2+)
Why is iron not excreted through urine?
Iron is not excreted through urine because the body tightly regulates iron levels by controlling absorption rather than excretion.
