Iris Growths

Question 1

Iris cyst

Answer 1

Uncommon unilateral lesions that can be primary or secondary in etiolgoy

Question 2

Primary iris cyst

Answer 2

Usually peripherally located and originate from the iris pigmented epithelium or the iris stroma
-they classically present as a globular, dark brown, lesion that transilluminates. They typically do not throw in size and do no cause symptoms

Question 3

Secondary iris cysts

Answer 3

Occur after truama, surgery, or from strong miotic medications. They are a result of ingrowth of the surface iris epithelium

Question 4

Iris nevus

Answer 4

Common condition that affects 50% of the general population. Resutls from the benign proliferation of malnocytes. They are pigmented, single or multiple lesions that are typically flat (or slightly elevated , almost always less than 3mm in size

Question 5

Lisch nodules

Answer 5

Small, round, lightly pigmented hamartoms that develop within 2nd or 3rd decade of lift; they are typically bilateral and located in the inferior half of the iris. Lisch nodules are present in 95% of cases of NF

Question 6

Koeppe nodules

Answer 6

Small, lightly colored iris nodules that are composed of inflammatory cells and are located on the pupillary border of the iris. They are associated with granulomatous uveitis

Question 7

Metastatic lesion of the iris

Answer 7

Rare, fluffy iris masses that most commonly arise from primary carcinomas of the breast, lung, or prostate. They usually occur after the primary location of cancer has been identified. Much more less common that’s chorodial metastatic lesions

Question 8

JXG

Answer 8

Benign, usuall symptomatic, yellow-orange nodules composed of vascularized and differentiated lipid containing histocytes. Appx 35% of cases occur at birth, and 71% of cases develop within the first year of life; only 10% of cases manifest in adulthood. Most resolve spontaneously by age of 5, and do not require treatment

Question 9

Iris cyst etiolgoy

Answer 9

Idiopathic

Question 10

What could iris cysts cause

Answer 10

Secondary glaucoma
-they are often located peripherally, they may cause angle closure and secondary glaucoma due to increased IOP; this is that most concerning threat to vision associated with iris cysts. Additional complications include obscuration of the visual axis and distortion of the pupil.

Question 11

What test should always be done on patients with iris cysts

Answer 11

Gonio to rule out angle invovlemtn

Question 12

Metastatic iris lesions are associated with

Answer 12

Pseudohypopyon
Anterior uveitis 
Hyphema
Iris rubeosis
Secondary glaucoma