IPE Flashcards
What are some important Q to ask in a dermatology history?
Is it changing
Any itching, swelling, fever, pain or discharge?
Any changes with joint, mouth, nails or scalp?
Any systemic changes?
Travel history
Sex history
Any changes in topical preparations
How would you describe the colour of a lesion?
- Erythema
- Purpura
- Hypopigmentation
- Hyperpigmentation
How would you describe a flat patch?
Macule
Papule >5mm
How would you describe a raised area of skin?
Papule v nodule v plaque
How would you describe a fluid filled area of skin?
- Vesicle v bulla
What are the red flag signs for skin lesions?
- Asymmetry
- Irregular border
- Two or more colours within the lesion
- Diameter >6mm
- Evolving
What are the different allergy tests that can be done
Skin prick tests - wheal formation - skin pierced and substance added - food allergen and pollen
Skin patch test - contact dermatitis - takes 96 hours
What are the salient features of a malignant melaoma?
UV exposure on pale skin
frequently metastasize to lymph nodes
Breslow depth predicts mortality based on invasion depth
Chemo and radiotherapy have minimal benefits – laser therapy and immunotherapy are common
What are the salient features of a SCC?
RF- acitinic keratosis, smoking,, previous skin cancer
May metastasize
May occur in long standing leg ulcers - Marjlon Ulcers
Bowen’s disease - SSC in situ - well demarkated scaly patch of slow growing area
surgical treatment
What is a BCC?
Most common skin cancer Rarely metastasize light exposed areas usually treated with wide base excision Initially a pearly flesh coloured papule with telangectasia that ulcerates leading to a central crater
What are some differentials for skin cancer lesions?
- Seborrhoeic keratosis - stuck on appearance - management is reassurance and removal
- Keratocanthoma - dome shaped erythematous base that develops over days and grow rapidly ( need biopsy to check)
-Acitinic keratosis - pre malignant - atypical keratocytes in the epidermis from chronic Uv exposure
May need Fluro-uracil creams and avoid the sun
What are cherry hemanigomas?
Campbel de morgan spots
Skin lesions which contain an abnormal proliferation of capillaries
non blanching and not on mucosal surfaces
no treatment needed
What is the pathophysiology of acne vulgaris and where is it seen?
Follicular epidermal proliferation –> colonisation by anaerobic bacterium and inflammation
Occurs mainly on the face, neck and back
How are the lesions in acne vulgaris described?
Comedones - white and black heads
Papules and pustules
Nodules
on erythematous base
Severe acne may result in ice pick and hypertrophic scars
What is the treatment of acne vulgaris?
Reassurance and advice about washing face
Benzoyl peroxide/ topical retinoids
Topical combination therapy - one of above and topical antibiotic
Oral Abx- tetracylcine
Could consider anti-androgen - dianette in females
Oral retinoid if scarring