Involvement of the hippocampus in memory

Question 1

Neuroimaging

Encoding task that manipulated stimulus similarity to enhance pattern separation process

• Reported increased activity in hippocampus during encoding task

Answer 1

Kirwan and Stark 2007

Question 2

Neuroimaging.

• Documented hippocampal activation during sucessful recollection of recently acquired information
• Evidence that the pattern completion process occurs in the hippocampus?

Answer 2

Eldridge et al 2000

Question 3

Functional neuroimaging

Sorted activity at encoding dependening on whether stimuli were subsequently remembered or forgotten

• Activity in left VLPFC and MTL at encoding predicted later successful remembering.

Answer 3

Wagner et al 1998

Question 4

Cued participants to perform one of two elaborative encoding tasks on words.- then asked them to recollect which encoding task they had carried out on each stimulus

• Activity in left VLPFC and hippocampus at encoding predicted subsequent successful recollection. (i.e. source memory)
• Activity in left perirhinal cortex predicted whether words were subsequently recognised as familiar (recognition memory- old or new?)