Investigation Results by Condition

Question 1

Addison’s (3)

Answer 1

1. Hyponatraemia
2. Hyperkalaemia

(both due to low aldosterone = low # of ENacs = low sodium reabsorption and low potassium excretion)

3. Hypoglycaemia

Question 2

Conn’s (Adrenal Adenoma) / Bilateral Adrenal Hyperplasia (both are primary hyperaldosteronisms) (4)

Answer 2

1. Hypokalaemia
2. Hypertension
3. Alkalosis
4. Raised Aldosterone

Question 3

Addisonian Crisis

Answer 3

Hyperkalaemic Metabollic Acidosis on ABG

Question 4

DeQuervains Thyroiditis

Answer 4

1. Initial Hyperthyroidism
2. Increased T4
3. Increased ESR
4. Globally Reduced I131 uptake
5. painFUL goitre

Question 5

Kleinfelter’s (2)

Answer 5

1. HIGH LH and FSH
2. LOW Testosterone

Question 6

Kallman’s (3)

Answer 6

LOW FSH, LH and Testosterone

Question 7

Cushing’s from Pituitary Adenoma (Dex Supp Test) (2)

Answer 7

1. ACTH: LOW / SUPPRESSED
2. Cortisol: LOW / SUPPRESSED

Question 8

Cranial / Central DI (Desmo supp test)

Answer 8

1. Urine Osm: LOW after water deprivation
2. Urine Osm: HIGH / NORMAL after Desmopressin

Question 9

Primary Hyperparathyroidism (3 bloods, 1 Radiological finding) (4)

Answer 9

Bloods:
1. Raised or (inappropriately given high Ca) Normal PTH
2. Hypercalcaemia
3. Low phosphate

X-Ray
4. “Pepperpot skull” - multiple defined lucencies in the skull