Introduction To The Nervous System Flashcards
What does the nervous system do?
Responds to stimuli
Transmits impulses
Controls every function in the human body
What are the basic functional units of the nervous system? What is their function?
Neurons
Responsible for signaling, responding to stimuli, transiting impulses, and information processing
What is the function of glial cells (glia)?
Support nervous system tissue
Help neurons wire together in the developing brain, nurture them in the adult brain, insulate axons, mop up dead cells, recycle used neurotransmitters and protect the brain from infection
What mental and regulatory functions are facilitated by neurons?
Awareness of self and surroundings
Memory, learning and speech
Muscular contraction and glandular secretion
What is a dendrite?
Receives and transmits impulses to the cell body
What is the cell body?
Receives nerve impulses from dendrites
What is the axon?
Transmits impulses away from the cell body
What is the function of neuronal cell bodies?
Contains nucleus
Maintain neuron integrity
What 2 components other then usual organelles does cytoplasm contain? What is their function?
Nissl bodies (endoplasmic reticulum) are prominent in the cytoplasm except where the axon emerges. They produce proteins
Neurofibrils are arranged longitudinally and are
involved in transport
What cellular components can lead to the formation of protein clumps in neurodengenerative diseases.
Neurofibrils
What is a unipolar neuron? Where are they found? How are they organized?
Axon is a single protoplasmic process
Located almost exclusively in spinal nerves and some cranial nerves
Cell bodies are organized in ganglia
What is a bipolar neuron? Where are they found?
Axon and 1 dendrite
Visual, auditory and vestibular pathways
What is a multipolar neuron? Where are they found?
Axon and multiple dendrites
Everywhere else in the nervous system
Describe the difference between dendrites and axons.
Dendrites impulse towards cell body
Axons impulse away from cell body, can have variable length
What is the significance of the morphological classifications of neurons?
Shapes help to maximize function
What are synapses?
Junction between the axonal ending and a muscle cell, gland, or another neuron
Junctional space is called the synaptic cleft
What carries impulses within a synaptic cleft?
Neurotransmitters which are manufactured and released by neurons, can be excitatory or inhibitory
What is the significance of polarization in synapses?
Allows impulse to travel
Impulse always travels from the axon to the next
neuron, muscle cell or gland
What is an excitatory synapse? Where are they found?
Enhances impulse production
Neuromuscular and neuro glandular synapse
Neuronal synapse
What is an inhibitory synapse? Where can they be found?
Hinders production of impulse
Neuronal synapse
What is anterograde axoplasmic transport?
Cell body nutrients are carried in a forward direction from the cell body to the termination of the axon
What is retrograde axoplasmic transport? What is the clinical significance?
Occurs from the distal end of the axon back to
the cell body
Enables return of used or worn out materials to the cell body for restoration
route by which toxins and viruses are transported into the CNS from the peripheral nervous system (ex: rabies)
What is the support tissue (glia) of the CNS?
Astrocytes
Oligodendrocytes
What are the support tissue (glia) of the PNS?
Schwann cells
capsular cells
What is the blood brain barrier? What is its function?
Permeability control system controlling passage between capillaries and the CNS parenchyma; related to tight junctions between endothelial cells.
What are oligodendrocytes? Function? Location?
Small
Form and maintain myelin
Wraps around axons to form tight spiral
Can surround cell bodies (no myelin)
Produces neurotrophic factors that promote growth of damaged factors
What are Schwann cells? Function?
Oligodendrocytes of the PNS
surrounds only one part of myelinated axon
What are capsular cells (satellite cells)?
Glial elements that surround neuronal cell bodies in sensory autonomic ganglia
Help regulate the neuronal chemical environment
What is the ratio of glial cells to neurons?
50:1
What is included in and the function of the CNS?
Brain and spinal cord
Receives, processes and acts on information in the environment
What is the PNS? How are connections made?
Connect CNS to areas outside nervous system
Connections are made via cranial no spinal nerves
Where does the spinal cord extend? What are its extensions?
Extends from the brain stem and through the neck and back
Peripheral extensions are spinal nerves
What are afferent pathways?
Carry info to the brain
Sensory
What are efferent pathways?
Carry info away from brain
Motor
In what NS are afferent and efferent pathways contained?
Both PNS and CNS
Describe the somatic nervous system.
Voluntary control of movements via skeletal muscles
Describe autonomic nervous system.
Control of smooth muscles, internal organs, muscle
including blood vessels, stomach, intestine, liver, kidneys, bladder, genitals, lungs, pupils, heart, and sweat, salivary and digestive glands
Unconscious, involuntary
What are the 2 division of the autonomic nervous system? What is their functions?
Sympathetic fight or flight
Parasympathetic rest and digest
What is blastulation in the development of the nervous system?
Single-layered structure formed after repeated
cleavage of a fertilized egg.
Epithelial covering encases the fluid filled cavity
What are astrocytes? What is their function?
Most numerous cells in CNS
Blood Brain barrier, electrolyte balance,
neurotrophic factors and removal of neurotransmitters from synaptic cleft
What is the function of oligodendrocytes?
Forms the myelin sheath
What is the function of Schwann cells?
Forms the myelin sheath (PNS)
Describe the structure of astrocytes and the function their provide.
Star shaped cell body with irregular processes
End-feet on surface of brain/spinal cord
◦ Form external limiting membrane (glial membrane)
Vascular end-feet form blood brain barrier by surrounding capillaries
◦ Selectively governs the passage of materials into the CNS via the circulatory system
What are some additional functions of astrocytes?
Electrolyte balance of CNS
Neurotrophic factors: promote growth of axons, necessary for survival
Remove certain neurotransmitters from the synaptic cleft
What support cells are highly susceptible to the formation of neoplasms?
Astrocytes
What is gastrulation in the development of the nervous system?
Blastula is reorganized into a multilayered (3) structure known as the gastrula.