Introduction to Renal Clearance Flashcards
1
Q
Is urea an overestimation or underestimation of GFR? Why?
A
Underestimation, because although urea is freely filtered, it is reabsorbed to a small extent.
2
Q
Is creatinine an overestimation of underestimation of GFR?
A
Overestimation, because although is it freely filtered, it is secreted to a small extent.
3
Q
What is the plasma creatinine clearance formula?
A
[(A)x(140-age)xweight]/(72xScr)
4
Q
What is A?
A
A constant in the creatinine clearance formula. 1 for males, .85 for females.
5
Q
Seriously though, what is the plasma creatinine clearance formula?
A
[(A)x(140-age)xweight]/(72xScr)
6
Q
What is the formula to determine clearance given a 24-hr urine?
A
CLcr=(Ucr)V/Pcr
V: Urine volume divided by 1440