Introduction to Renal Clearance Flashcards

1
Q

Is urea an overestimation or underestimation of GFR? Why?

A

Underestimation, because although urea is freely filtered, it is reabsorbed to a small extent.

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2
Q

Is creatinine an overestimation of underestimation of GFR?

A

Overestimation, because although is it freely filtered, it is secreted to a small extent.

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3
Q

What is the plasma creatinine clearance formula?

A

[(A)x(140-age)xweight]/(72xScr)

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4
Q

What is A?

A

A constant in the creatinine clearance formula. 1 for males, .85 for females.

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5
Q

Seriously though, what is the plasma creatinine clearance formula?

A

[(A)x(140-age)xweight]/(72xScr)

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6
Q

What is the formula to determine clearance given a 24-hr urine?

A

CLcr=(Ucr)V/Pcr

V: Urine volume divided by 1440

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