Introduction to physiology -pharmacology Flashcards
What is pharmacology?
The study of the effects of drugs on the function of living systems
what is a drug?
A drug can be defined as a chemical substance of known structure other than a nutrient or an essential dietary ingredient, which when administered to a living organism, produces a biological effect
what is pharmacokinetics ?
What the body does to the drug (pharmacokinetics)
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Absorption, distribution, metabolism, excretion (ADME), elimination, bioavailability
what is pharmacodynamics ?
What the drug does to the body (pharmacodynamics)
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Drug target, mechanism of drug action, drug affinity, drug efficacy, drug selectivity, potency, concentration-response relationship, drug safety, drug tolerance
Definitions
of life?
Reproduction
Movement
Metabolism
Excitability
Adaptibility
Organ systems for COMMUNICATION ?
Nervous
system
Endocrine
system
Organ systems for TRANSPORT ?
Cardiovascular
system
Respiratory
system
Gastrointestinal system
Urinary
system
Organ systems for MOVEMENT ?
Locomotor system
Organ systems for REPRODUCTION ?
Reproductive system
Organ systems for DEFENSE ?
Immune system
Homeostasis?
Temperature
changes
Blood
volume
Oxygen
availability shortage
Energy
turnover shortage
Physical
activity
Gravitational
changes
Micro
organisms
what does the cardiovascular system do?
Transportation of:
*
O
2
*
CO
2
*
Nutrients
*
Waste
*
Hormones
*
Heat
Protection against
infection
Stabilization of:
*
pH
*
Ions
*
Body fluids
*
Osmolarity
Create pressure from
force
*
Filtration
The cardiac cycle ?
1.
Diastole. SL valves (the
pulmonary valve and the aortic
valve) closed, the AV valves (the
mitral valve and the tricuspid
valve) open, and the whole heart
is relaxed.
2.
Diastole. The atrium contracts,
and blood flows from atrium to the
ventricle.
3.
Systole. “ Isovolumic
contraction” is when the
ventricles begin to contract,
the AV and SL valves close.
4.
Systole. “Ventricular
ejection,” is when the
ventricles are contracting and
emptying, and the SL valves
are open.
5.
Systole. Isovolumic relaxation
time”, pressure decreases, no
blood enters the ventricles, the
ventricles stop contracting and
begin to relax, and the SL valves
close due to the pressure of blood
in the aorta.
Conduction system of the heart ?
1.sinoatrial node (SA)
2.atriventricular node ( AV)
3.atrioventricular bundle ( bundle of Hiss)
4. Right and left bundle branches
5. Conduction myofibers ( punkinje fibers)
ECG QRS= ?
Ventricular depolarization
Atrial repolarization