Introduction To Pharmacology Quiz

Question 1

A drug that binds to a receptor and produces a biological response that mimics the response to the endogenous ligand is known as:

Answer 1

An agonist

Question 2

The substance binding to one receptor subtype as an agonist and to another as an antagonist is called:

Answer 2

Agonist-antagonist

Question 3

In which controlled substance schedules is codeine found?

Answer 3

Controlled substances schedules II and V

Question 4

No risk in animal studies, and well-controlled studies in pregnant women are not available. it is assumed there is little to no risk in pregnant women.

Answer 4

B

Question 5

A risk to human fetus has been proven. Risk outweigh benefits. Should be avoided during pregnancy.

Answer 5

X

Question 6

Animal studies indicate a risk to the fetus . Controlled studies on pregnant women are not available. Risk versus benefit of the drug must be determined.

Answer 6

C

Question 7

A risk to the human fetus has been proven. Risk versus benefit of drug must be determined. It can be used in life threatening conditions

Answer 7

D

Question 8

No risk to fetus. Studies have not shown evidence of fetal harm

Answer 8

A

Question 9

A drug that permits an easy recognition of the drugs belonging to one group and to comprehend and to correlate their pharmacological effects is called a:

Answer 9

Prototype drug

Question 10

Oxidation if a drug:

Answer 10

Involves the cytochrome P450

Question 11

Reduction occurs:

Answer 11

In the endoplasmic reticulum

Question 12

If a drug has a half life of 2hrs and directly after IV administration the serum concentration is 100mg/ml. What is the serum concentration of the drug after 6hrs?

Answer 12

12.5mg/ml

Question 13

The biological half life is the

Answer 13

estimate of the time required for a drug quantity to be reduced by half in a particular body compartment

Question 14

Testosterone is an example of the a drug altering the pace of ongoing activity through which if the following methods?

Answer 14

Replacement

Question 15

Pilocarpine is an example of the a drug altering the pace of ongoing activity through which if the following methods?

Answer 15

Stimulation

Question 16

An Antagonist is:

Answer 16

A drug which has no intrinsic activity at the receptor but has affinity for the receptor

Question 17

Pharmacokinetics is

Answer 17

The study of absorption, distribution, metabolism and excretion of drugs

Question 18

What does affinity mean?

Answer 18

A measure of how tightly a drug binds to receptor

Question 19

Target proteins which a drug molecule bind to are

Answer 19

Ion channels, carriers, and receptors

Question 20

What is characteristic of the oral route ?

Answer 20

Absorption depends on GI tract secretion and motor function

Question 21

The term “biotransformation” includes the following:

Answer 21

Process of physiochemical and biochemical alteration of a drug in the body

Question 22

Half life (t1/2) doesn’t depend on:

Answer 22

Time of drug absorption

Question 23

Define the term ‘receptor’

Answer 23

Active macromolecular components of a cell or an organism which a drug molecule has to combine with in order to elicit its specific effect

Question 24

All the following statements about efficacy and potency are true EXCEPT:

Answer 24

Efficacy is the maximum effect of a drug

Question 25

Which routes completely by-passes first-pass metabolism?

Answer 25

Intravenous administration

Question 26

Which of the following represents “Pregnancy Category D”?

Answer 26

Evidence of risk to human fetus, benefits outweigh risks in serious conditions

Question 27

A patient is prescribed a medication to be taken every day other day , applied to their right ear which of the following abbreviations would be shown on the prescription.

Answer 27

q.o.d, AD

Question 28

If an agonist can produce submaximal effects and has moderate efficacy it’s called

Answer 28

Partial Agonist

Question 29

A competitive agonist is a substance that:

Answer 29

Binds to the same receptor site and progressively inhibits the agonist response