Introduction To Pharmacology Quiz Flashcards
A drug that binds to a receptor and produces a biological response that mimics the response to the endogenous ligand is known as:
An agonist
The substance binding to one receptor subtype as an agonist and to another as an antagonist is called:
Agonist-antagonist
In which controlled substance schedules is codeine found?
Controlled substances schedules II and V
No risk in animal studies, and well-controlled studies in pregnant women are not available. it is assumed there is little to no risk in pregnant women.
B
A risk to human fetus has been proven. Risk outweigh benefits. Should be avoided during pregnancy.
X
Animal studies indicate a risk to the fetus . Controlled studies on pregnant women are not available. Risk versus benefit of the drug must be determined.
C
A risk to the human fetus has been proven. Risk versus benefit of drug must be determined. It can be used in life threatening conditions
D
No risk to fetus. Studies have not shown evidence of fetal harm
A
A drug that permits an easy recognition of the drugs belonging to one group and to comprehend and to correlate their pharmacological effects is called a:
Prototype drug
Oxidation if a drug:
Involves the cytochrome P450
Reduction occurs:
In the endoplasmic reticulum
If a drug has a half life of 2hrs and directly after IV administration the serum concentration is 100mg/ml. What is the serum concentration of the drug after 6hrs?
12.5mg/ml
The biological half life is the
estimate of the time required for a drug quantity to be reduced by half in a particular body compartment
Testosterone is an example of the a drug altering the pace of ongoing activity through which if the following methods?
Replacement
Pilocarpine is an example of the a drug altering the pace of ongoing activity through which if the following methods?
Stimulation
An Antagonist is:
A drug which has no intrinsic activity at the receptor but has affinity for the receptor
Pharmacokinetics is
The study of absorption, distribution, metabolism and excretion of drugs
What does affinity mean?
A measure of how tightly a drug binds to receptor
Target proteins which a drug molecule bind to are
Ion channels, carriers, and receptors
What is characteristic of the oral route ?
Absorption depends on GI tract secretion and motor function
The term “biotransformation” includes the following:
Process of physiochemical and biochemical alteration of a drug in the body
Half life (t1/2) doesn’t depend on:
Time of drug absorption
Define the term ‘receptor’
Active macromolecular components of a cell or an organism which a drug molecule has to combine with in order to elicit its specific effect
All the following statements about efficacy and potency are true EXCEPT:
Efficacy is the maximum effect of a drug
