Introduction to pharmacology of the nervous system (3) Flashcards
1
Q
What is a drug?
A
a chemical substance that interacts with a specific target within a biological system to produce a physiologic effect
2
Q
What are the 4 main classes of drug target?
A
- receptors
- enzymes
- transport proteins
- ion channels
3
Q
What type of drug target does salbutamol act on?
A
receptor
4
Q
What type of drug target does atorvastatin act on?
A
enzyme
5
Q
What type of drug target does citalopram act on?
A
transport protein (SSRI)
6
Q
What type of drug target does amlodipine act on?
A
ion channel
7
Q
What is pramipexole?
A
dopamine receptor agonist- treats Parkinson’s
8
Q
What are off-target side effects?
A
when drugs bind to targets that aren’t the intended ones (bc similar structure)
9
Q
What causes side effects?
A
- dependent on the dose of drug administered
- other targets in the same tissue or other tissues
- same target but in other tissues
