Introduction To Pharmacology Flashcards
What do we regulate in blood plasma?
Oxygen
Glucose
Ions
Volume
What do we regulate in interstitial fluid?
Glucose
Ions
What do we regulate in intracellular fluid?
ATP
Glucose
Ions
Volume
What is total body water?
42 L
~ 60%
How much water in blood plasma?
3L
How much water in interstitial fluid?
13L
- liquid surrounding cells
How much water in transcellular fluid?
1L
- CSF, lymph ect
How much water in intracellular fluid?
25L
What is the osmolality?
290 mOsm
What’s the distribution of ions ECF vs ICF?
ECF = more Na+, Cl-, Ca2+
ICF = more K+
What is amphipathic?
Have a region of polar and non-polar.
- Phospholipid bilayer
What is the cell membrane’s permeability?
Impermeable to large & charged.
Permeable to hydrophobic (O2, CO2, steroid hormones)