Introduction to Nutrition – Undernutrition Flashcards

1
Q

What proportion of the western population is overweight and what proportion is obese?

A

50% are overweight

25% are obese

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2
Q

What proportion of the global population live below recommended nutritional needs?

A

1/3 (<1200 kcal)

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3
Q

What hierarchy describes the needs of humans?

A

Maslow’s Hierarchy of Needs

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4
Q

Describe the balance between obesity and undernutrition.

A

Prevalence of obesity is about the same as the prevalence of undernutrition (27%)

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5
Q

What measurement is commonly used for undernutrition?

A

Arm circumference and arm fat - they pinch the skin in the middle of the upper arm and measure the thickness

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6
Q

What is body weight a reflection of?

A

Total cell mass

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7
Q

Why is body weight not reflective of nutritional status in some cases of malnourishment?

A

Some malnourishment will cause oedema, which will confound the body weight result.

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8
Q

What is usually set as the recommended intake of nutrients?

A

RNI - reference nutrient intake - this is 2.5 standard deviations above the estimate average intake

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9
Q

What are the roles of vitamin C?

A

Anti-oxidant - involved in converting Fe3+ to Fe2+

It is also important in the formation of stable collagen fibres.

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10
Q

What is a deficiency in vitamin C?

A

Scurvy

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11
Q

What three components make up energy expenditure?

A

Resting energy expenditure (BMR)
Adaptive thermogenesis
Exercise

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12
Q

State some fates of acetyl CoA.

A

Amino acids, Fatty acids, ketone bodies, pyruvate, TCA cycle

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13
Q

What are the main stores of energy?

A

Glycogen
Adipose Tissue
Muscle

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14
Q

State three hormones regulating appetite.

A

Leptin, Ghrelin, PYY3-36

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15
Q

What are some signs of undernutrition?

A
Weight loss
Loss of subcutaneous fat
Muscle wasting
Peripheral oedema
Hair Loss
Chronic infections 
Poor wound healing 
Recurrent pulmonary infections
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16
Q

State three differences between Marasmus and Kwashiorkor.

A

Marasmus has no oedema
Marasmus has good appetite
Marasmus rarely causes any mental changes

17
Q

What happens to energy expenditure as you starve?

A

Decreases - fuel utilisation by almost all organs (except the brain) decreases

18
Q

What is another name of vitamin B1 and what is its deficiency called? State some symptoms.

A

Thiamine
Deficiency = Beri Beri
Symptoms = fatigue + severe lethargy

19
Q

Why is this disease important in medicine today?

A

It is associated with chronic alcoholics with an inadequate diet (Wernicke-Korsakoff Syndrome)
Associated with gastric bypass surgery

20
Q

What is niacin and what does a deficiency in niacin cause?

A

Vitamin B3 - used to produce nicotinamide for NADP and NAD

Deficiency = Pellagra