INTRODUCTION TO HEMATOLOGY Flashcards
Introduce the my fellow students to the study of blood and its relevance to the diagnosis of diseases.
Hematology Involves
1.The study of Cellular constituents of the blood
Hematology also involves
2.The number of concentration of cells
Hematology also involves
3.The relative distribution of various types
of cells
Hematology also involves
4.The study of structural or biochemical abnormalities of blood cells that result in disease.
Blood is
A Tissue
Blood is examined in practically
Examined in practically every phase of medical practice, including blood forming tissues.
Blood is examined whenever
Whenever even the slightest suggestion of a disorder affecting the blood directly or indirectly
Certain observations of peripheral blood universally regarded as
Indispensable to the examination of all patients.
Blood Volume for average sized adult male is
Approx 5 liters of blood
( T/F ) Size matters when determining the Volume of Blood
T
( T/F ) On average, for an adult male it is about 75 mL/kg [ 5.625L] , for woman 65 mL/kg [4.875L].
T
What percentage is Blood in the Human Body?
Accounts for 8% of the human body weight, with an average density of approximately 1,060 kg/m3
Functions of blood Include
1.Supply of oxygen to tissues.
Functions of blood Include
2.Supply of nutrients such as glucose, amino acids, and fatty acids.
Functions of blood Include
3.Removal of waste such as carbon dioxide, urea, and lactic acids.
Functions of blood Include
4.Immunological functions. Circulation of white blood cells, and detection of foreign material by antibodies.
Functions of blood Include
5.Coagulation.
Functions of blood Include
6.Messenger functions. The transport of hormones and the signaling of tissue damage.
Functions of blood Include
7.Regulation of body pH.
Functions of blood Include
8.Regulation of core body temperature.
Functions of blood Include
9.Hydraulic functions
Blood is made up of?
- Plasma (a fluid of complicated and variable composition)
2. Suspended cells
Suspended Cells include
- Mainly erythrocytes (red blood cells).
- Leukocytes (white blood cells).
- Platelets (thrombocytes).
Percentage Volume of Plasma in Blood
Plasma constitutes 55% of blood
Percentage Volume of water in Plasma
Plasma is mostly water 92% by volume
What other components does Plasma Contain?
- Proteins
- Glucose
- Mineral ions
- Hormones
- Carbon dioxide.
The name of the main Protein in Plasma
Albumin
How does Albumin the main Protein in Plasma function?
Functions by regulating the colloidal osmotic pressure of blood.
When blood coagulates, the resultant fluid after separation of the clot called
Serum.
How is Serum different from plasma?
Serum differs from plasma mainly by loss of the protein fibrinogen, converted to insoluble fibrin strands in the process of coagulation.
Serum and Plasma used for many tests in
- Clinical Chemistry.
2. Immunology.
Hemoglobin is denoted by
Hb or Hgb
Define Hemoglobin
The iron-containing oxygen-transport metalloprotein in the red blood cells (RBCs)