Introduction to Endocrinology

Question 1

What is the basic mechanism of a Guanylyl Cylcase receptor pathway?

Answer 1

Guanylyl Cylase –> cGMP –> PKG

Question 2

What are the two domains for steroid receptors, include their functions

Answer 2

E Domain: Steroid hormone binding domain

C Domain: Highly conserved DNA binding domain, has zinc fingers

Question 3

Growth Hormones typically bind to what type of receptor?

Answer 3

Tyrosine Kinase Associated Receptors

Question 4

What is the mechanism of action of tyrosine kinase associated receptors?

Answer 4

They associate non-covalently to receptors with tyrosine kinase activity