Introduction To Dosage Forms And Routes Of Administration Part C Flashcards
1
Q
What are some examples of dosage forms?
A
Tablets Solutions Capsules Bulk Powders Syrup Eye drops Ear drops Powders in sachets Gels Ointments Suppostories Creams Linctus Suspensions (into the rectum) Meltlets
2
Q
Factors affecting choice of dosage form:
A
- different administration routes require different dosage forms
- need to consider the physicochemical properties of the API (stability via the administration route)
e. g. IV, requires liquid, sterile/ pulmonary - device to deliver to the lung - different patient populations have different needs (temporary needs exist too)
- time onset of action e.g. i.v = seconds, tablets = minutes to hours
3
Q
What is reconstitution and why is it done?
A
- mixing water with a powder to produce a liquid
- as when the liquid is formed it has a short expiration date which will not cover the period of time the medicine needs to be taken
4
Q
What are the steps for reconstitution?
A
- boil tap water + let it cool to room temperature
- shake the bottle with the medicine gently to loosen the powder
- use the measuring syringe to draw up the volume of water required (stated on the bottle) + squeeze it into the bottle
- shake the bottle unito all the powder has dispersed
- check the bottom of the bottle to ensure no powder remains
- storage in the fridge after checking storage requirements
- discard any medicine left after finished course (taken to the local pharmacy)