Introduction to Bone and Soft Tissue Flashcards

1
Q

How is the musculoskeletal system divided into

A
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2
Q

What does the human skeleton consist of

A

206 bones in adults

270 in children

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3
Q

What are the functions of the skeleton

A

Support - helps you stand up

Protection - protects your vital organs

Movement - works with muscles so you can get around

Mienral storage - stores calcium and phosphate

Produces blood cells - bone marrow

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4
Q

What is the process of endochondral ossification

A

Hyaline cartilage formed from chondroblasts

Development of long bone from hyaline cartilage

Forms a ring of tissue around it - perichondrium

Condrocytes forms a calcified matrix

Matrix forms a primary ossification center with a nutrinet artery-centre of long bones

End of long bones - secondary ossification center

Junction between secondary and primary is epiphyseal plate

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5
Q

What are bones made up of

A

Cells

Matrix

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6
Q

Type of bone cells

A

Osteogenic cells - stem cell

Osteoblast - bone forming, secreted asteoid, catalyse mineralilsation

Osteocyte - Mature bone cell and formed when osteoblast becomes imbedded in its secretions, sense mechanical strain

Osteoclast - Bone breaking, phagocytosis of bone, derived from bone marrow

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7
Q

Where do you fine bone cells

A

Osteogenic cells - deep layers of periosteum

Osteoblast - growing portions of bone, periosteum and endosteum

Osteocytes - entrapped in matrix

Osteoclasts - bone surfaces and at sites of old, injured or unneeded bone

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8
Q

Composition of bone matrix

A
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9
Q

What are the bone types

A

Immature bone - first bone that is produced, laid down in a woven manner, mineralised and replaced by matured bone

Mature bone - mineralized woven bone, lamellar structure. relatively strong

Cortical mature bone - dense, suitable for weight baring

Cancellous mature bone - spongy honeycomb, not suitable for weight baring

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10
Q

Diagram of cancellous bone

A
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11
Q

Organisation of compact/cortical bone: osteons

A

Haversian Canal: Vertical structures containing artery, vein, lymphatic system

Surrounding the bone are concentric lamellae laid down by osteoblast

Become osteocytes when they get trapped

In between the haversion systems are the volkmans canals

Lacunae - small spaces containing osteocytes

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12
Q

Structure of long bone

A
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13
Q

How do bones growth

A
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14
Q

What happens in interstital growth

A

Happens at the physis (physeal plate)

Zone of elongation in long bone

Contains hyaline cartilage

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15
Q

What happens in appositional growth

A

Deposition of bone beneath the periosteum to increase thickness

Ridges in periosteum create groove for blood vessels

Periosteal ridges fuse forming endosteum-lined tunnel

osteoblasts build new concentric lamellae inward towards center of tunnel forming a new osteon

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16
Q

How does calcium hydroxyapatite help

A

Structural support

17
Q

How do we classify joints

A

Fibrous - radius and ulna, tibia and fibia, skull (sutures, syndesmosis, interosseous membrane)

Cartilaginous - integral struture, synchondorses eg spine, symphyses eg pubic

Synovial - most common

18
Q

Functional types of synovial joints

A

Plane

Hinge joint - only move in one plane

Condyloid

Pivot

Saddle

Ball and socket

19
Q

What are the characteristics of a synovial joint

A

Characteristed by joint capsule

Articular capsule - outer

Synovial membrane - inner

Synovial fluid into synovial cavity - secreted by synovial membrane and hyaline cartilage

Low friction high lubrication

20
Q

How are synovial joints stabilised

A

Bone surface congruity - stable between bones

Ligaments - stop bones moving from extreme directions - (MORE stability LESS mobility), poor stability, risk of dislocation, excessive ligament laxity - hypermobility - greater risk of injury

Muscles - tendons can stabiles

21
Q

Comparison of hip and shoulder stability

A
22
Q

What is the process of intramembranous ossification

A

Initiated by mesenchymal stem cells

Differentiate into osteoblasts

Osteoblast lay down osteoid - trapped

Osteoid calcifised form spicules which form trabeculae

Blood vessels condense and for periosteum - fibrous sheet that covers bone

Formation of lamellar bone formed around spongey bone. Has regular alignment of collagen