Introduction to Biochemistry Flashcards
-Swedish founder of biochemistry.
-Studied the chemical composition of matter in mid 1700.
CARL SCHEELE
prove the fallacy that biochemicals can only be
produced by living organisms by producing urea by heating ammonium cyanate.
FRIEDRICH WOHLER
Who formulated the cell theory in 1840?
Matthias Schleiden and Theodore Shwann
Discovered chromosomes
Walther Flemming
German scientist who coined the word “biochemistry”
Carl Neuberg
found that extracts from yeasts could bring about
fermentation of sugar into alcohol in 1897.
Eduard and Hans Buchner
Proposed the Krebs cycle of the TCA in 1937.
Hans Krebs
Identify DNA as information molecules in 1944
Avery, Macleod, and Mccarty
- propose the double helical structure of
DNA - Propose the central dogma of Biology
- James Watsons and Francis Crick
-Francis Crick
a chemical substance found within a living organism
Biochemical substance
Biochemical Substance are divided into 2 groups. What are those?
- Bioinorganic Substances
- Bioorganic substances
-Substances that do not contain carbon
-includes water and inorganic salts
- constitutes over two-thirds of
the mass of the human body
BIOINORGANIC SUBSTANCE
-Substances that contain carbon
-Include carbohydrates, lipids, proteins, and nucleic acids
-make up only about one-fourth of body
mass
BIOORGANIC SUBSTANCES
-Present in plant and animal cells
-Compose of 50-95% H2O and 1%ions
BIOMOLECULES
Carbon based molecule that are covalently bonded to itself or other elements like H, O, N, S, P.
ORGANIC MOLECULES
One important organic molecule is the
HYDROCARBON
-Biomolecules are derived from HC
-Non-polar
-Hydrophobic
HYDROCARBON
Two broad types of biomolecules
-small biomolecules/building blocks
-macromolecules
4 families of small molecules are found inside the cell
- Amino acids
- Sugar
- Fatty Acids
- Nucleotides
3 major parts of amino acids
1.Amino group
2.Carboxyl Group
3.R group
Example of polypeptides
- Transport proteins
- Structural proteins
- Enzymes
-AA is less than 50 (and are called peptide)
- are called proteins
-Short polypeptides
-Long polypeptides
The bond connecting the amino acids in the polypetide are called peptide bonds and also______
Amide bond
-are called carbohydrates
-the most abundant organic molecules in nature
SUGAR
-basic unit of sugar
-known as simple sigar
MONOSACCHARIDES
functional group of monosaccharides
-Polyhydroxyl Aldehyde
-Polyhydroxyl Ketone
Example of sugars
-Glucose
-Fructose
-Ribose
-Deocyribose
polymer containing large amount of monosaccharides
Polysaccharides
Example pf polysaccharides
- Glycogen
- Starch
- Cellulose
-Monocarboxylic acid
- usually contains an even number of carbon atoms
- are components of Lipids
FATTY ACIDS
types of Fatty acids:
-single bonded
-one or more bonds
-Saturated FA
-Unsaturated FA
Example of:
Saturated FA
Unsaturated FA
-Palmitic acid
-Oleic Acid
Also known as fat and oil
Triacylglycerols