Introduction to Autosomal Single-Gene Inheritance

Question 1

These diseases are due to mutations in one or both members of a pair of autosomal genes or to mutations in genes on the X or Y chromosome (sex - linked inheritance).

Answer 1

Single-gene disorders (Mendelian disorders)

Question 2

Mendelian disorders show characteristic patterns of inheritance in ____.

Answer 2

family pedigrees

Question 3

Within each chromosome, the genes have a strict order, each gene occupying a specific location or ____.

Answer 3

locus

Question 4

T/F. Autosomal genes are present in pairs, one member being of maternal and one member of paternal origin.

Answer 4

True

Question 5

If both members of a gene pair (i.e. alleles) are different, then the individual is ___ for that locus.

Answer 5

heterozygous

Question 6

Any gene - determined characteristic is called a ___.

Answer 6

trait

Question 7

If a trait is expressed in the heterozygote, then the trait is ____, whereas if it is only expressed in the homozygote, it is ____.

Answer 7

dominant; recessive

Question 8

The effects of both alleles may be seen in the heterozygote, and these are called ____ traits.

Answer 8

codominant