Introduction lecture Flashcards
1
Q
Dose is…
A
the amount of drug taken at any one time
2
Q
Efficacy is…
A
the ability of the drug to cause physiologic response when it interacts with a receptor
3
Q
Potency (Affinity) is…
A
the amount of drug necessary to produce an effect of a given magnitude
4
Q
Therapeutic index
A
TI = TD50 / ED50
the ratio of the dose that produces toxicity to the dose that produces a clinically desired response
5
Q
Therapeutic window
A
Measures drug’s safety
Larger values indicates a wide range margin between doses that are effective and doses that are toxic
