Introduction Flashcards
What are the two prominent theories for aging?
Damage theory
Programmed death theory
What is the focus of damage theory?
Focus on environmental stress that occurs to cells
What are the three pieces of damage theory?
Oxidative stress - increase in amount of or damage from oxidate species in mitochondria or cyp450 functioning
Wear-and-tear - cells are working hard and get worn out
Telomere - cells have a finite number of replication before telomeres shorten, deeming them ineffective at cell division
What does programmed death theory focus on?
Aging has a biological clock
What are the pieces of programmed death thoery
Molecular theory - related to genetics being programmed at certain ages to signal cell death
System decline theory - neuroendocrine (HPA axis) and immune systems decline, they are less adaptive to stress and insults (infectious, cancerous)
What are the leading causes of death?
Accidents Alzheimer's Diabetes Heart dz HTN Stroke
What is the different between frailty and dysfunction
To what degree is a senior able to function without assistance
What are the measurements of functionality?
Activities of Daily Life
Instumental Activities of Daily Life
What is ADL?
Self-care tasks such as personal hygiene, dressing/undressing, eating, toileting, ambulating, transferring from bed to chair
What is IADL?
Activities that allow an individual to live independently; such as light housework, preparing meals, taking medications, shopping for essential items, using the phone, and managing money
What ages are considered elderly?
65-84
What ages are considered very elderly?
85+
What is a geriatric syndrome
Costly and debilitating clinical problems common in geriatric patients which are not neatly categorized as specific disease states or is restricted to certain organ systems
What are common geriatric syndromes?
Frailty Incontinence Delirium Sleep disorders Falls, dizziness, syncope Pressure ulcers, elder mistreatment
What are the I’s of geriatrics?
Immobility Isolation Incontinence Infection Inanition (malnutrition) Impaction Impaired senses Instability Intellectual impairment Impotence Immunodeficiency Insomnia Iatrogenesis