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Anesthesia > Introduction > Flashcards

Introduction Flashcards

1
Q

Anesthesia is

A

Loss of feeling or sensation (including pain)
Partial or complete
Drug induced; intentional
Used to perform surgery or other painful procedures
Reversible
Local, regional or general

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2
Q

Local anesthesia

A

Loss of feeling or sensation to a specific area due to local desensitisation of a peripheral nerve bed
Freezing, line blocks

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3
Q

Regional anesthesia

A

Loss of feeling or sensation to a large portion of the body (such as a limb, lower half of the body, abdomen)
Due to desensitisation of spinal nerves and/or peripheral nerve bundles
Spinal block, epidural

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4
Q

General anesthesia

A

Anesthesia due to depression of the CNS
Comal-like state; affects the entire body
Patient neither perceives nor recalls noxious stimuli
Increased risk of adverse effects

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5
Q

Tranquilization means

A

Reduces anxiety and produces sense of tranquillity
Anti-anxiety, calm and chillout
Reduces the ability respond to a stimulus
There is no change in the ability to perceive pain

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6
Q

Sedation is

A

More profound that tranquilization and produces drowsiness and/or hypnosis
The sedatives reduce anxiety, reduce the ability to respond to stimulus
Sedatives also decrease sensation of pain
Animal is CONSCIOUS
3 levels
Light
Moderate
Heavy

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7
Q

Hypnosis, narcosis is

A

Greater degree of CNS depression
Degree of consciousness is noticeably affected; patient is entering unconscious state
Will learn that this overlaps with stage 1 and 2 of general anesthesia

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8
Q

Surgical anesthesia

A

Patient is unconscious
There is no perception of pain
Significant CNS depression

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9
Q

Analgesia

A

Relief of pain without loss of consciousness

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10
Q

Analgesic

A

A drug that relieves pain

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11
Q

Balanced anaesthesia (aka multimodal anesthesia/analgesia) is and includes

A

Using multiple drugs in combination
In smaller doses than if only using one drug on its own
To obtain appropriate CNS depression to perform a specific procedure
Includes
Premed
Induction agent
Maintenance anesthesia
Analgesia (pre- and intra- operative)

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12
Q

Benefits of balanced anesthesia

A

Limits adverse effects of each individual drug
Maximize the benefits of each drug
Accounts for motor, sensory (PAIN), reflex and mental aspects of the nervous system

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13
Q

The anesthetic protocol must take into account:

A

Patient
Procedure
Facilities available
NOTE: your anesthetic protocol is always changing between patients…. and sometimes for the same patient

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14
Q

What is the RVTs role in anesthesia

A

Preparation, operation and maintenance of anesthetic equipment
Administration of anaesthetic agents
Endotracheal intubation
Patient monitoring
Planning
Patient
Equipment and materials
Patient assessment
Premedication
Surgical fluids
Induction
Surgical prep
Maintenance anesthesia
Recovery (period when anesthetic drug is removed and vital return to normal, animal is conscious)
Postoperative analgesia

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15
Q

What does the RVT do to plan anesthesia

A

Patient
Estimates, required diagnostics, pre-surg medications
Organizing with owner (incl fasting requirements)
Consents
Equipment and materials
Drugs, anesthetic equipment, surgical equipment
Patient assessment
Weight, TPRs
Asses for pre-procedure mentation and pain
Any pre-anesthetic diagnostics (bloods,rads)
\

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16
Q

What does the RVT do to patient assessment before anesthesia

A

Weight, TPRs
Asses for pre-procedure mentation and pain
Any pre-anesthetic diagnostics (bloods,rads)

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17
Q

What does the RVT do for premed

A

Calculating doses, administration medications
Assessing degree of sedation after administration
Responding to adverse reaction to sedation/premed

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18
Q

What does the RVT do for surgical fluids

A

Setting up surgical fluids
Catheter placement
Calculating fluid rates based on fluid plan

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19
Q

What does the RVT do for induction of anesthesia

A

Calculating and administering injectable anesthetic dose
Endotracheal; intubation
Assessing depth of anesthetic
Patient monitoring

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20
Q

What does the RVT do for maintaining anesthesia

A

Operating anesthetic machine
Oxygenation
Delivery of inhalant drugs
Ensuring fluids and thermosupport
Patient assessment
Assessing depth of anaesthesia
Assessing patient vitals
Monitoring and responding to drug effects; ability to rapidly respond in case of overdose/arrest
Differentiating pain from other stress

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21
Q

What does the RVT do for recovery of anesthesia

A

Patient monitoring and assessment
Extubation, assessing for pain/other physiological stress
Requesting appropriate analgesia/sedation if indicated
Providing non-pharmacological comfort and care

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22
Q

What does the RVT do for postoperative analgesia

A

Patient monitoring
Assessing for pain and comfort
Calculating and administering analgesics and ancillary support (i.e., PT, IV fluids, antibiotics, nutrition)

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23
Q

Fundamental challenges, inherent risks of anesthesia

A

Very narrow therapeutic index
Consequences of a calculation or administration error → may be serious
Vital signs and indicators and anaesthetic depth
MUST BE closely monitored
Accurate interpretation of visual, tactile, and auditory info from the patient, anaesthetic equipment, and monitoring devices
Comprehensive understanding of the significance of physical parameters (ex. HR,RR, reflexes) and machine generated data (ex. BP, O2 sat’n)
Potential for patient harm during administration of anaesthetic is relatively high
Competence and confidence are earned through
Study, practice,, persistence, caring attitude, dedication to excellence

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24
Q

What is essential to know for anesthesia

A

Pharmacology of common drugs
Desired effects
Expected SIDE EFFECTS
Unacceptable side effects
Pharmacy laws
Controlled drugs
Dose calculations
Normal patient physiology
What is not “normal” is automatically abnormal
Also know how “normals” change when under the influence of anaesthetic drugs
How to recognize and respond to adverse effects

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25
Q

Preanesthetic assessment should include

A

Patient history
Signalment
Current and past illness
Medications currently being administered
Allergies or drug reactions
Status of preventive care
Physical examination
Haematology/biochemistry
Anesthetic plan

26
Q

The anesthetic protocol should incldude

A

Pre-anesthetic treatment
Premed
Induction
Maintenance
Analgesia
Blocks
Emergency drugs
Monitoring/special equipment
Recovery/post-procedure analgesia plan

27
Q

Functions of the nervous system

A

Sensory
Integrating
Motor

28
Q

Two types of nervous sytem

A

A central nervous system (CNS)
Brain and spinal cord
Peripheral nervous system (PNS)
Nerves that link the CNS with the rest of the body

29
Q

Neuron

A

Basic functional unit of the nervous system. Composed of a cell body, dendrites, and an axon. Initiate nerve impulses, and also conduct them.

30
Q

Neurotransmitters

A

Chemical released by the presynaptic neuron that diffuses across the synaptic cleft, binds with the receptor on the postsynaptic membrane, and stimulates or inhibits the postsynaptic neuron

31
Q

Synapse

A

Junction between two neurons or between a neuron and target cell

32
Q

Receptor

A

A specialized protein to which neurotransmitters bind
“lock and key”

33
Q

Nerve impulse

A

Wave of cell membrane depolarization that travels from the point of stimulus down the length of a nerve cell process
Conducted along a nerve fibre by the “flipping” of electrical charges across the cell membrane (depolarization), followed quickly by “unflipping” of the electrical charges (repolarization)

34
Q

Local anesthetics

A

Drugs injected to block the conduction of sensations
Ex. Lidocaine
Prevents sensory nerves from depolarizing despite stimulation

35
Q

Epidural anesthesia

A

Anesthetic agents are injected into the space outside the spinal cord dura mater to produce large areas of local anaesthesia
Block depolarization waves through spinal nerves thus removing the perception of pain from the part of the body they supply
The body can more readily maintain normal autonomic function during this type of anaesthesia

36
Q

Neurotransmitters classifications

A

Excitatory
Inhibitory
Both
Acetylcholine, Catecholamines (norepinephrine, epinephrine, dopamine), GABA (gamma-aminobutyric acid) and glycine

37
Q

Excitatory neurotransmitters are

A

Have an excitatory effect on the postsynaptic membrane when combine with the receptor

38
Q

Inhibitory neurotransmitters are

A

Tend to depress or decrease depolarization of other neurons or target tissues

39
Q

Neurotransmitters and receptors of the somatic nervous system

A

Conscious or voluntary control of skeletal muscles

40
Q

Sympathetic nervous system (SNS) does what

A

Fight or flight
Neurotransmitter: catecholamines; primarily norepinephrine but also epinephrine and dopamine
Adrenergic neurons

41
Q

Adrenergic neurons in the SNS

A

Alpha 1: found on blood vessels, and cause vasoconstriction of the skin, GI tract and kidney
Beta1: increase HR and force of contraction
Beta2: bronchodilation

42
Q

Parasympathetic nervous system (PNS) does what

A

Rest and restore
Neurotransmitter: acetylcholine
Cholinergic neurons
Nicotine
Muscarine

43
Q

Anesthetic agent is

A

Any drug to induce a loss of sensation w/ or w/o unconsciousness

44
Q

Adjunct is

A

Drug that is not a true anesthetic, but is used during anesthesia to produce other desired effects
Sedation, muscle relaxation, analgesia, reversal, neuromuscular blockade, or parasympathetic blockade

45
Q

Classifications of anaesthetic agents

A

Route of administration
Time period of administration
Priciple effect
Chemistry

46
Q

Classifications of anaesthetic agents by route of admin

A

Inhalant
Injectable
Oral

47
Q

Classifications of anaesthetic agents by time period of admin

A

Preanesthetic medication
Induction agent
Maintenance agent

48
Q

Classifications of anaesthetic agents by principle effect

A

Local anaesthetic
General anesthetic
Sedatives
Tranquilizers
Muscle relaxants
Neuromuscular blockers
Anticholinergic agents
Reversal agents

49
Q

Drug classifications based on “chemistry”

A

Anticholinergics
sedatives/tranquilizers
Phenothiazines
Benzodiazepines
Alpha2- agonists
Opioids
Propofol
Etomidate
Alfaxalone
Barbiturates
Dissociatives
Guaifenesin
England anaesthetics

50
Q

Angonist and antagosnist are

A

After administration, most drugs are distributed throughout the body by the blood. Each drug binds to specific receptors in one or more “target tissues”. After binding to specific receptors, the drug stimulates the receptor, causing one or more specific effects.

51
Q

Agonists work by

A

Bind to and stimulate tissue receptors

52
Q

Antagonists work by

A

Bind to, but do not stimulate receptors
Reversals
Competitively bind to receptors and displace the corresponding agonist, blocking further action

53
Q

Partial agonists work by

A

Bind to and partially stimulate receptors

54
Q

Agonist-antagonists work by

A

Bind to more than one receptor type and simultaneously stimulate one and block at least one

55
Q

Drugs in anesthesia work by

A

Mimicking inhibitory neurotransmitters that turn down nerve function- Turning “on” the off signals
OR
Can bind to and block action of the naturally occurring neurotransmitters- Blocking the “on” signals

56
Q

Agonists = Drugs that bind to nerves and turn ON

A

Drugs that have the same activity as naturally occurring neurotransmitters
Bind to and “TURN ON”; effect is to increase a naturally occurring response
Ex: diazepam which binds to and turns on the neurons that “turn down” the brain
Turning on the “OFF” switch

57
Q

Antagonist = drug that block activity of normal neurotransmitters

A

Drugs that bind to and block the naturally occurring response at the nerve synapse
Decreases or prevents an action
Most commonly act by binding to receptors and blocking neurotransmitters from binding
Blocking the “On” switch

58
Q

All of the drugs used in general anaesthesia are nerve depressants:

A

General anesthetics depress CNS function, especially the brain
Regional anesthetics are directed at peripheral nerve bundles and/or spinal segments
Local anaesthetics block peripheral nerves
Tranquilizers and sedatives depress CNS function to a lesser degree

59
Q

CNS depressants are

A

Aka central-acting drugs
Tranquilizers, sedatives and general anesthetics
Act directly on the brain
Wide-ranging effects; usually also affect the ANS
Low therapeutic index
All the the ability to cause death
Tranquilization→ sedation→ narcosis/hypnosis→ loss of consciousness→ brain stem shut-down → death

60
Q

Effect of anesthesia on the autonomic nervous system

A

Drugs also influence the ANS
May be a directed side-effect of the drug
Part of turning on the parasympathetic response (rest and digest)
Especially sedatives and tranquillisers

61
Q

Effects of turning up the PS response are

A

Decreased RR, bronchoconstriction
Peripheral vasodilation
Decreed HR and stroke volume
Increased bronchial and GI secretions
Miosis

62
Q

Effects of turning up the SN response are

A

Increase HR
Increase RR
Dilate of bronchioles; increase air blow
Pupils dilate, mydriasis
Decreased Gi motily and blood flow to skin
Increased blood to muscle
Decreased diameter of kidney blood vessels

Anesthesia (8 decks)

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