Introduction Flashcards
it is a quantitative science that is concerned with the measurement of biologically important substances in body fluids
clinical chemistry
primary purpose of clinical chemistry
facilitate the correct performance of analytic procedures that yield accurate and precise information, aiding patient diagnosis and treatment
he predicted that chemical analysis of body fluids altered by disease would play an important role in the investigation of pathogenesis
gabriel andal
described the application of chemistry to pathology and therapeutics as being of the greatest importance to the medical practitioner
alfred b garrod
stressed the practical diagnosis value of chemistry
henry bence jones
did not believe that chemical studies were relevant to clinical medicine
armand trousseau
he advised those entering medicine not to lose time “in acquiring too extensive a knowledge of chemistry”
armand trousseau
the year when average medical student had barely a nodding acquiantance with chemistry and could not use a microscope
1870 (USA)
wrote the first book in English to carry the title Clinical Chemistry
Charles henry ralfe
developed quantitatve analytical methods for urine analytes
otto knut folin
developed volumetric gas measuring apparatus
donald dexter van slyke
the year when the most common problem cited by doctors was the large number and unintelligent use of laboratory tests ordered in hospitals
1932
one physician in 1944 described the approach to patients as what?
five minute history followed by five day barrage of special tests
it was the tribute to ivar christian bang
when van slyke characterized ivar as the complete clinical chemist
biologically important substances in the body fluids, the one being measured
analyte
common analytes being measured
ions, salts and minerals & small organic molecules & large macromolecules
example of ions, salts and minerals
potassium, chloride, sodium, calcium, magnesium
examples of small organic molecules
glucose, cholesterol, urea, lactic acid
examples of large macromolecules
albumin, lipase, amylase, total protein
most common biological fluid collected
blood
supernatant of anticoagulated blood
plasma
supernatant of clotted blood
serum
the usual values for a healthy population
reference interval
importance of lab exams in cc
to confirm diagnosis, to rule out or in a certain disease, to monitor therapy, to establish prognosis
roles of medtech in cc lab
familiar with techniques, good backround in instrumentation and maintain quality control
process by which disease develops
pathogenesis
study and dx of diseases
pathology
treatment
therapheutics
gives doctors info abt patient’s body fluids balance
metabolic tests
likely outcome or course of disease
prognosis
