Introduction Flashcards

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1
Q

Invented genetic mapping

A

A.H Sturtevant

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2
Q

What happens in recombination?

A

Genetic material is exchanged between two homologous chromosomes during cell division, leeading to genetic diversity. A new combination of alleles is produced.

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3
Q

Homologous phenotype and example

A

Homologous phenotype are traits or characteristics that have the similar function or appearance in different species due to shared ancestry. Such as the forelimbs of vertebrates of other animals; batwings or whale flippers have the same bone structures despite having different functions.

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4
Q

Tell me about the law of dominance

A

It states that one allele can mask the expression of the other. The dominant allele will be manifested while the recessive trait remains hidden unless both alleles are recessive.

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5
Q

Person who observed pea characteristics. (provide the year)

A

Gregor Mendel - 1865

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6
Q

Differentiate diploid from haploid

A

Diploid are cells that carries two copies of the gene whereas haploid are cells that carries one copy of the gene; applicable in gametes

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7
Q

People who proposed Chromosome Theory of Inheritance

A

Walter Sutton and Theodor Boveri - 1902

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8
Q

What nitrogenous base is absent in DNA?

A

Uracil

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9
Q

Discovered DNA

A

Friedrich Miescher- 1869

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10
Q

Proposed the chromosome theory

A

Theodor Boveri and Walter Sutton- 1902

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11
Q

Constructed the genetic map

A

A.H Sturtevant- 1913

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12
Q

Determined the structure of DNA

A

James Watson, Francis Crick, Rosalind Franklin, and Maurice Wilkins- 1953

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13
Q

First used plasmid to clone DNA

A

Herb Boyer and Stanley Cohen- 1973

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14
Q

Discovered interruptions (introns) in genes

A

Phillip Sharp, Richard Roberts, and others - 1977

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15
Q

Determined the base sequences of the genomes of two bacteria

A

Craig Venter, Hamilton Smith - 1995

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16
Q

Cloned a sheep (Dolly) from an adult sheep udder cell

A

Ian Wilmut and colleagues - 1997

17
Q

Used “next generation” sequencing to obtain the first sequence of an Asian (Han Chinese) human.

A

Jian Wang and colleagues - 2008