Introduction

Question 1

what is pharmacology?

Answer 1

the study of chemicals that interact with the body

Question 2

what is pharmacodynamics?

Answer 2

what a drug does to the body e.g. biological effects

Question 3

what is pharmacokinetics?

Answer 3

what the body does to a drug e.g. absorption

Question 4

what is a ligand?

Answer 4

molecule that binds to another molecule

Question 5

what is a drug/chemical agonist?

Answer 5

a drug/chemical that activates a receptor and causes a response. Posses both affinity and efficacy

Question 6

what is a drug/chemical antagonist?

Answer 6

a type of drug which binds to a receptor but does not activate it, thus blocking the action of the agonist by binding to the same receptor. Posses affinity not efficacy

Question 7

what is affinity?

Answer 7

binding step. It is the strength of association between the receptor and ligand

Question 8

what happens to the dissociation rate with low affinity?

Answer 8

fast dissociation rate

Question 9

what happens to the dissociated rate with high affinity?

Answer 9

slow dissociation rate

Question 10

what is efficacy?

Answer 10

activation step. Ability of an agonist to evoke a cellular response

Question 11

what happens to the response if low efficacy?

Answer 11

low response

Question 12

what happens to the response if high efficacy?

Answer 12

bigger response

Question 13

what is the orthosteric site?

Answer 13

binding site of receptor

Question 14

what does competitive antagonist mean?

Answer 14

both agonist and antagonist want to bind to the same site

Question 15

what does non-competitive antagonism mean?

Answer 15

agonist binds to orthosteric site and antagonist binds to allosteric site