Introduction

Question 1

What is virology?

Answer 1

study of viruses and viral diseases

Question 2

What is a virologist?

Answer 2

Person who studies viruses

Question 3

What is veterinary virology

Answer 3

study of viruses in non-human animals

Question 4

Why is vet virology important? (3)

Answer 4

high sickness and death
financial losses
zoonoses

Question 5

Are viruses living?

Answer 5

no, non-living entities

Question 6

Components of a virus

Answer 6

nucleic acid genome (DNA/RNA) w/ protein coat
sometimes envelope

Question 7

Do viruses possess organelles?

Answer 7

No, no standard organelles

Question 8

Why are viruses referred to as obligate intracellular parasites?

Answer 8

rely on host cell, hijacks and uses cell to assemble themselves and the next generation

Question 9

Do viruses divide?

Answer 9

No, they use an assembly line using parts of the host cell.

Question 10

Virion

Answer 10

complete virus particle w/ RNA/DNA with protein coat or envelope
EXTRACELLULAR INFECTIVE FORM

Question 11

Virus

Answer 11

any aspect of infectious agent, includes:
virion, inactivated virus particle, viral nucleic acid and protein in infected cell

Question 12

Viroid

Answer 12

infectious particle SMALLER than any of the known viruses. usually plant diseases

Question 13

What genome does a viroid possess?

Answer 13

extremely small circular RNA with NO PROTEIN COAT

Question 14

Is a viroid a virus?

Answer 14

NO IT DOESNT HAVE A PROTEIN COAT

Question 15

What did Edward Jenner do?

Answer 15

inoculated cowpox into a healthy 8 yr old who became immune to smallpox
FIRST RECORDED VX HX

Question 16

What did Louis Pasteur do?

Answer 16

injected dried potassium hydroxide and infected rabbit brain into two bitten boys - Both lived
RVX

Question 17

Describe a Chamberland Filter

Answer 17

pores smaller than bacteria, pioneered viral discovery

Question 18

Explain the Tobacco Mosaic Virus experiment

Answer 18

diseased tobacco leaf crushed, passed through filter
debris placed on healthy leaf- remained healthy
cell filtrate on healthy leaf - dead leaf

Question 19

Who did the Tobacco Mosaic Virus Experiment

Answer 19

Dmitri Ivanoski

Question 20

What was the first animal virus passed through filter?

Answer 20

Foot and Mouth Disease

Question 21

Who discovered the cause of foot and mouth disease

Answer 21

Loeffler and Frosch

Question 22

Who discovered the spread of Yellow Fever? What was it spread by?

Answer 22

Walter Reed, mosquitoes

Question 23

Who discovered the first oncogenic virus

Answer 23

Peyton Rous

Question 24

What was the first oncogenic virus discovered?

Answer 24

Rous Sarcoma Virus

Question 25

Who invented the electron microscope?

Answer 25

Ruska and Knoll

Question 26

First virus seen under electron microscope?

Answer 26

Tobacco Mosaic Virus

Question 27

What virus was propagated and in what medium?

Answer 27

fowlpoxvirus in embryonated hen eggs

Question 28

Who propagated the first virus?

Answer 28

Woodruff, Goodpasture and Burnet

Question 29

Tissue culture

Answer 29

growing cells in an artificial environment

Question 30

What did Sanford et. al do?

Answer 30

culture of isolated mammal cells in 1948

Question 31

What did Enders et al. do?

Answer 31

grow poliovirus in cell culture

Question 32

What is Dulbecco and Vogt do?

Answer 32

Complete and plaque assay for first animal virus-polio

Question 33

Eradication

Answer 33

complete elimination from defined geographic region

Question 34

What is the only eradicated animal virus

Answer 34

Rinderpest in 2001