Introduction Flashcards
1
Q
What are the three different approaches to disease and what do they focus on?
A
- 3 different ways to approach disease
- medical - patient focused; targeting the pathogen, worried about health outcomes, trying to target the within host pathogen and mitigate the response to the disease
- epidemiologists - population patterns of infection and what statistically predicts the outcome of the disease given presumed causal factors
- disease ecology - predict the course of infection into the future- very process focused, evolutionary dynamics; seeks to predict the course of the disease
2
Q
When was the first meeting of the epidemiological society of london?
A
1825 - first meeting of epidemiological society of London
3
Q
Where did the soceity get the data from?
A
- data from slaves, soldiers, all around the British empire
- that allows them for deep understanding of the disease
4
Q
Who was the founding member of the society?
A
John Snow - founding member of epidemiological society of London
5
Q
What did John Snow do?
A
- in 1854 - cholera outbreak in Soho - nobody knows how cholera is transmitted so nobody knows what’s happening
- John snow says that because it is a disease of digestive system it i s probably fecal/oral and nobody believes him
- he goes of to prove his hypothesis
- breaks down the outbreaks of cholera based on where people are getting their water from - from upstream where contaminated water is coming from - people don’t get that much disease
- then he went to the pumps and interviewed people
- he identifies the pump as a source of epidemic and famously removes the handle of he pump which stopped the outbreak
6
Q
What happened in Haiti after the earhtquake?
A
- shortly after the tsunami there was a epidemic of cholera
- very surprising cuz they didn’t have cholera before
- either sanitary disruption or it was brought from somewhere
- They found that most outbreaks were present downstream of the UN misson
- they sechenced the strain and then they found that the strain was close to the strain from nepal which the volunteeres from the UN camp were from
7
Q
What is disease ecology?
A
Disease ecology - understand what drives pathogen transmission and spread over space and time
8
Q
What happened with the foot and mouth disease outbreaks?
A
- foot and mouth disease outbreaks
- scientists start using ecological models on disease statistics
- the number of infected farms are gonna be doubled every 9 days
- they also found out how the disease is transmitted like air and vets moving between farms