Introduction Flashcards
What is angina
Heavy chest pressure due to decreased oxygen
What are the types of angina
Stable: angina due to emotional stress or exertion and gets better with rest or NTG
Unstable: does not get better with rest or ntg
Prinzmetals: occurs at rest
What are other names of prinzmetals
Variant, vasospasmatic
What is meant by ischemia
Reduced blood flow
What are the treatment options for stable angina
Nitrate, BB, CCB, ranexa
What is the first line for chronic stable angina?
BB
What are long acting nitrates
Nitrodur
Isosorbide mononitrate
What are rapid acting nitrates
Nitrostat
Nitrolingual
Nitromist
Gonitro
What are treatment options for unstable angina
Ntg
Bb (iv)
What are the treatment options for vasospasmatic
Ntg
Ccb
Bb with isa
App
Acebutolol
Pindolol
Penbutolol
What is the other name for b1 sel bb and what are those
Cardioselective
Amebbba
Atenolol
Meto
Esmo
Biso
Betaxo
Bystolic
Acebutolol
What are the adverse for bb
Fatigue
Brady
Depression
Worsening pad and raynauds
Bronchoconstriction
Can bb be used for vasospasmatic angina
No
Why bb is first line for chronic angina
Decrease( hr, afterload, contractility, oxygen demand)
What QT prolonging drugs
Quinidine
Dofetilide
Sotalol
Thioridazine
Ziprasidone
What are the uses for ccb
Raynauds
Htn
1st line for vasospasmatic angina
Svts
Maintenance of stable angina
What are dhp ccb that are fda approved for angina
Amlodipine, nifedipine er, nicardipine
Why cant we use nicardipine ir for angina
Bcuz more reflex tachy, headache, peripheral edema, flushing
What are the long acting dhp and non ccb used for vasospasmatic angina
Verapamil, diltiAzem, amlodipine
What is ranolazine used for
Chronic stable angina ( refractory)
What are the contraindications for ranolazine
- Prolongs qt. Caution with existing qt due to hypokalemia
- Hepatic impairment
- Qt prolonging drugs
- Dont use if pt on 3a4 inh