INTRODUCTION Flashcards

1
Q

Three disciplines devoted to drugs

A

Pharmacology
Pharmacognosy
Medicinal chemistry

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2
Q

Two constituents of drugs:

A

Active constituents

Inert constituents

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3
Q

Compounds that are responsible for the therapeutic effect.

A

Active constituents

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4
Q

Constituent with no pharmacologic activity

A

Inert constituents

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5
Q

Three secondary constituents

A

Heredity
Ontogeny
Environmental Factors

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6
Q

Study of the biochemical pathways leading to the formation of secondary constituents used as drugs

A

Drug biosynthesis

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7
Q

Made papyrus ebers

A

George Ebers

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8
Q

Content of papyrus ebers

A

Use of plant & animals in medicine

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9
Q

Egyptian document

A

Papyrus ebers

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10
Q

Book authored by Dioscorides

A

De Materia Medica

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11
Q

Content of De Materia Medica

A

Use of 600 medicinal plants

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12
Q

Method of processes of preparing formulas containing animal & plant drugs

A

Galenical pharmacy

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13
Q

Name of Galen

A

Claudius Galen

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14
Q

Who coined the term Pharmacognosy

A

C. A. Sydler

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15
Q

Words where pharmacognosy is derived from

A

pharmakon - “drug”

gnosis - “knowledge

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16
Q

First one to use the term Pharmacognosy in literature

A

J.A. Schmidth

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17
Q

French Pharmacist and made quinine w/ the collaboration of Pelletiere

A

Joseph Caventou

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18
Q

Phytochemist who discovered codein and narcotine

A

Pierre Robiquet

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19
Q

German Pharmacist who discovered hyoscyamine

A

Rudolf Brandes

20
Q

Discovered atropine w/ the collaboration of Rudolf Brandes

A

Philip Geiger

21
Q

Father of Botany

A

Theophrastus

22
Q

Plant grows in their native countries

A

Indigenous

23
Q

Grew in foreign land other than their native countries

A

Naturalized

24
Q

Substances that are found in nature that comprise whole plants & herbs

A

Natural substances

25
Single substance/s which are considered as chief constituents of the drugs
Derivatives
26
Vegetable or animal drugs that consist of natural substances that have undergone only the presence of COLLECTION & DRYING.
Crude drugs
27
Three classifications of drug constituents
Natural Semi-synthetic Totally synthetic
28
Classification of drug constituents that are directly obtained from nature
Natural constituents
29
Classification of drug constituents from chemical modification of a natural constituent
Semi-synthetic
30
Ex: Camphor from Camphor Plants What classification of drug constituent?
Natural constituent
31
Ex: Camphor < pinene < pine trees What classification of drug constituent?
Semi-synthetic
32
Classification of drug constituent that manufactures from chemical synthesis
Totally synthetic
33
5 ways of preparation of crude drugs
``` Collection Harvesting Drying Curing Garbling Packaging, storage, preservation ```
34
What to do in the collection of crude drugs?
Select the species to cultivate
35
Two ways of harvesting of crude drugs
Manual labor | Mechanical devices
36
What does drying of species lower?
Bacterial growth Fungi growth Hydrolysis
37
Method of enhancing the properties of the active ingredient
Curing
38
Physical process of removing extraneous material
Exposure of the drug to 65C Temperature Methyl Bromide Chloroform
39
Simplest form in preventing insect attacks & other form of destruction
Exposure of the drug to 65C Temperature
40
Use of methyl bromide in preservation of drugs
Fumigation of large lots of crude drugs
41
Amount of chloroform to control insect attack
Few drops
42
5 Methods of Evaluation of Crude Drugs
``` Biological Chemical Microcopic Morphological Physical ```
43
4 classifications of drugs
Morphologic Taxonomic Pharmacologic Chemical
44
Classification of drug that is based on the part used
Morphologic
45
Classification of drug that is based on the relationship or phylogeny
Taxonomic
46
Classification of drugs that are based on therapeutic activity
Pharmacologic
47
Classification of drugs that is based on the chemical class of the constituents
Chemical classification