Intro To Urinalysis Flashcards
Most frequent chemical analysis performed on urine; used for detection and monitoring of DM
Glucose
What is the white color in Hazardous Material Classification
Specific Hazard
Lysis of red blood cells
Hemoglobinuria
Measure of the density of dissolved chemicals in the urine specimen
Urine SG
Paired with Bilirubin to determine Liver Disease
Urobilinogen
Located within Bowman’s Capsule and forms the beginning of renal tubule
Glomerulus
Causes of Alkaline Urine
Diet high in fruits and vegetables
What is the change in the bilirubin of unpreserved urine, and it’s cause
Decreased, exposure to light/photo oxidation to biliverdin
The substance to be reabsorbed must combined with a carrier protein
Active Transport
Harm or Injury associated with the hazard
Risk
Extuingishing materials of Class A fire type
Wood, paper, and clothing
30 secs reading time in Reagent strip
Bilirubin
Glucose
Evident if there is an injury in the urinary tract
Blood
Type of urine preservative that is used for drug analyses
Sodium Flouride
An ultrafiltrate of plasma
Urine
What is the red hazard in Hazardous Material Classification
Fire Hazard
Nitrite (Reagent strip) Basis of Test
ability of certain bacteria to reduce nitrate to nitrite
Type of urine preservative that prevents bacterial growth and metabolism
Boric Acid (almost all acids)
It is any object with the potential to cause harm
Hazard
Reagent Strip (Glucose Oxidase) Reactions principle
Double sequential enzyme reaction
Uses a urine strip reader, or a urine analyzer in which a machine will do the chemical testing on your behalf.
Automated Reagent Strip
Buffering capacity of blood depends on
Biocarbonate (HCO3-) ions
It consists of a coil of approximately eight capillary lobes
Glomerulus
Abnormal volume of protein associated with Proteinuria
Greater than 30mg/dL or 300mg/L
What gives urine its yellow color; considered the most predominant pigment seen in fresh samples
Urochrome
Average daily urine output
1,200mL
Screening test for Bence Jones Protein
Solubility test
Aromatic odor
Normal
Source of Sharp Hazards
Needles, lancets, and broken glass
Decrease in urine output
Oliguria
Bleach odor
Contamination
60 secs reading time in Reagent Strip
Nitrite
Urobilinogen
Protein
pH
Blood
Ttpe of urine specimen that is used to produce accurate quantitatively results
24-hour Specimen
Surrounds the proximal and distal convoluted tubule
Peritubular Capillaries
Type of Diabetes wherein there is a decrease in insulin or decrease function of insulin
Diabetes Mellitus
It controls the regulation of the flow of blood to and within thr glomerulus
Renin-Angiotensis-Aldosterone System
pH of first morning specimens
5.0 to 6.0 (slightly acidic during the morning)
Bilirubin (Reagent strip) Principle
Diazo reaction
Pressure resulting from the smaller size of efferent arteriole
Hydrostatic pressure
The test most commonly associated with tubular secretion and renal blood flow
P-aminohippuric acid (PAH) test
It is often the first function affected in renal disease
Tubular Reabsorption Capability
Blood (Reagent Strip) Color Reaction
yellow- green – blue
Blood (Reagent Strip) Principle
Pseudoperoxidase activity of hemoglobin
Familial benign hypercalcemia
Blue urine
Soft, clear plastic bags with hypoallergenic akin adhesive attached to the genital area
Pediatric Specimen
Cause of pale yellow urine
Polyuria
DI and DM
DIlute random specimen
Non-reversible spontaneous decarboxylation product of diacetic acid
Acetone
Water is removed by
Osmosis
Cause of pink / red urine color
RBCs
Hemoglobin
Myoglobin
How many percent does acetone occupy in ketones
2%
How to check for urine color
Good light source
White background
Look down, well lit room
The more yellow, the more ________ it is
Acidic
Clear urine with positive chemical test for blood; muscle damage
Myoglobin
Consist of 85% of nephrons, located within the cortex of kidney, main function is removal of waste and reabsorption
Cortical Nephron
What is the change in the nitrite of unpreserved urine, and it’s cause
Increased, multiplication of nitrate-reducing bacteria
Cause of blue-green urine color
Methylene blue
Most random urine SG
1.015 to 1.030
The temperature not necessary of refractometer
15C to 38C
Primary organic component of urine
Urea
Relies on volume displacement; not recommended by CLSI
Urinometry
What are the cellular structures of the Glomerulus
Capillary wall membrane
Basement membrane
Visceral epithelium of bowman’s capsule
Source of Chemical Hazards
Preservatives and Reagents
Patients were deprived of fluids for 24 hours prior to measuring specific gravity
Fishberg test
Process that provides documentation of proper sample identification from the time of collection to the receipt of laboratory results
Chain of Custody (COC)
Hemoglobinuria
Clear red
Fruity sweet odor
Ketones
You will compare a strip to a color chart attached to the canister where the urine strips are placed, then compare and determine the concentration of a substance.
Manual Reagent Strips
Indicative of Liver Disease
Bilirubin
Final adjustment of the urinary composition
PCT or DCT
Distal Convoluted Tubule
Source of Electrical Hazards
Ungrounded or wet equipment; frayed cords
The liquid part of the blood
Plasma
Causes of Acidic Urine
Diet high in meat protein and with some fruits such as cranberries
What is the renal threshold of glucose
160mg/dl to 180mg/dl
Blood enters the capillaries of the nephrons through the
Afferent Arteriole
Represent multiple complex, state-of-the-art chemical reactions
Reagent Strips
Extinguishing material of Class K fire type
Grease, oils, and fats
What is the blue color in Hazardous Material Classification
Health Hazard
Immediate reabsorption of essential substance from the fluid
PCT or DCT
Proximal Convoluted Tubule
Presence of albumin in urine above the normal level but below the detectable range of conventional urine dipstick methods
Microalbuminuria
Specific Gravity (Reagent strip) Reagent
Multistix: Poly (methyl vinyl ether/maleic anhydride) bromthymol blue
Chemstrip: Ethyleneglycoldiaminoethylethertetraacetic acid,
bromthymol blue
Odor of freshly voided urine
Faint Aromatic
How many percent are the solutes in a normal urine composition
5%
Renal Functions
Renal blood flow
Glomerular filtration
Tubular reabsorption
Tubular secretion
Ketone (Reagent strip) Principle
Based on sodium nitroprusside (nitroferricyanide) reaction
Major serum protein found in the urine
Albumin
Cause of green urine color
Pseudomonas infection
Determines the concentration of dissolved particles by measuring refractive index; its principle is refractive index
Refractometer
Accurate pH measurement; Used in patients with disturbances of acid-base balance
pH Electrode
Cause of brown or black urine color
Malignant melanoma
Melanin
Melanogen
What is the change on the bacteria of unpreserved urine, and it’s cause
Increased, multiplication
Confirmatory for Bence Jones Protein
Serum Electrophoresis/IE
More accurate evaluation of renal concentrating ability; its principle is changes in colligative properties by particle number
Osmolality
How many percent does Beta-hydroxybutyric acid occupy in ketones
78%
Primary method used for the chemical examination of urine
Reagent Strips
Sweaty Feet odor
Isovaleric Acidemia
Most vulnerable part of drug testing program
Drug Specimen Collection